Lipids & Polymers

N-(Boc-PEG3)-N-bis-(PEG3-Amino-Tri-(Propargyl-PEG2-ethoxymethyl)-methane) is a crosslinker consisting of six propargyl groups and a t-Boc protected aminooxy group. The propargyl groups can form triazole linkage with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry. The protected amine can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research use only.

Hyaluronic Acid, MW 25,000 is comprised of hyaluronic acid that has been is functionalized with a terminal carboxylic acid through an amide bond. It is the most abundant glycosaminoglycan in the body, being an important component of several tissues throughout the body. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond. Reagent grade, for research use only.

4arm-PEG-alkyne, MW 2,000 is a 4-branched molecule with propargyl groups that can be linked to azide-containing biomolecules via Click Chemistry. The hydrophilic polyPEG linker increases the water solubility of the compound. Reagent grade, for research use only.

4arm-PEG-alkyne, MW 20,000 is a 4-branched molecule with propargyl groups that can be linked to azide-containing biomolecules via Click Chemistry. The hydrophilic polyPEG linker increases the water solubility of the compound. Reagent grade, for research use only.

8-arm PEG-GAS, MW 40,000 is an eight arm succinimidyl glutaramide activated polyPEG. The succinimidyl glutaramide group is a good leaving group and commonly reacts with amine nucleophiles at pH 7 to 9. Reagent grade, for research use only.

8-arm PEG-SCM, MW 10,000 is an eight arm succinimidyl carboxyl methyl ester activated polyPEG. The succinimidyl carboxyl methyl ester group is a good leaving group and commonly reacts with amine nucleophiles at pH 7 to 9. Reagent grade, for research use only.

LA-PEG-NHS, MW 1,000 is a polyPEG liner that contains a lipoic acid group and a terminal NHS group. The NHS group can participate in reactions with primary amine groups to form amide bonds. The hydrophilic polyPEG chain increases the water solubility of the compound in aqueous environments. Reagent grade, for research use only.

Mal-PEG-SCM, MW 1,000 is a polyPEG liner that contains a maleimide group and a terminal succinimidyl carboxyl methyl ester group. The maleimide group will react with a thiol group to form a covalent bond. The succinimidyl carboxyl methyl ester group is a good leaving group and commonly reacts with amine nucleophiles at pH 7 to 9. Reagent grade, for research use only.

Mal-PEG-SCM, MW 2,000 is a polyPEG liner that contains a maleimide group and a terminal succinimidyl carboxyl methyl ester group. The maleimide group will react with a thiol group to form a covalent bond. The succinimidyl carboxyl methyl ester group is a good leaving group and commonly reacts with amine nucleophiles at pH 7 to 9. Reagent grade, for research use only.