PEG

Biotin-PEG4-amide-Alkyne is a polyethylene glycol (PEG)-based linker primarily used for synthesizing PROTACs[1].

Biotin-PEG4-hydrazide, a biotin-labeled polyethylene glycol (PEG)-based hydrazide compound, is used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Biotin-PEG8-amine is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.

Bis-PEG23-endo-BCN, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Bis-PEG25-NHS ester is a cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs) [1].

Bis-propargyl-PEG11, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-aminooxy-amide-PEG4-propargyl is a non-cleavable 4-unit polyethylene glycol (PEG) linker commonly used in the synthesis of antibody-drug conjugates (ADCs)[1].

Boc-aminoxy-PEG4-acid is a PEG-based linker for PROTACs, designed to connect two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-C1-PEG3-C4-OBn (PROTAC Linker 15) is a PEG-based PROTAC linker used in the synthesis of various PROTACs, including PROTAC SGK3 degrader-1. PROTACs consist of two distinct ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase, while the other specifically interacts with the target protein, enabling selective degradation of target proteins via the intracellular ubiquitin-proteasome system[1].