Unlocking Insights with Precision Biomarkers Profiling
Recognized as a center of excellence for biomarker studies, Tebubio’s Contract Research Services Laboratory empowers you to identify, measure, and understand the role of your targets in any biological process.
Our biomarker solutions, leveraging antibody array technology, can be seamlessly integrated into fully customized projects—including advanced cell models for added precision and relevance.
Every project is overseen by a dedicated PhD-level expert, ensuring your research is handled with expert care and tailored to deliver optimized results.
Unlock the Power of Biomarker Discovery with Tebubio
At Tebubio, we provide cutting-edge solutions for biomarker discovery to empower your research. From targeting a single biomarker to screening up to 8000 human, 2808 mouse, and 1500 rat proteins, our platform delivers precision and scalability across a variety of sample types, including:
- Serum, plasma, culture supernatant
- Biological fluids, cell lysates, and tissue lysates
Our expertise spans critical research areas such as secretome analysis, inflammation studies, angiogenesis, apoptosis, growth factors, post-translational modifications, cytokine storms, phosphorylation, disease-focused arrays and much more…
Advanced Biostatistics and Bioinformatics Analysis
Our biostatistics and bioinformatics experts go beyond data collection to uncover key insights from your samples:
- Profiling and clustering: Techniques like Heatmaps and PCA plots reveal patterns and inherent structures in your data.
- Differential expression analysis: Pinpoint biomarkers showing significant changes between conditions.
- Pathway enrichment analysis: Dive deeper into biological processes with GO and KEGG analyses, uncovering how experimental conditions affect pathways and networks.
We can analyze data generated in-house or your existing data sets, tailoring every step to your research needs.
Comprehensive Biomarker Quantification
Quantify biomarkers with precision across species:
- 1200 human, 640 mouse, and 282 rat proteins
- Workable with a broad variety of sample types, including serum, plasma, culture supernatants, biological fluids, cell lysates, and tissue lysates.
Our solutions extend to other species for diverse research requirements.
Functional Analysis: Understand Mechanisms of Action
Once biological processes are identified, Tebubio offers functional analysis services to explore the mechanism of action:
- Binding assays
- Inhibitor/activator screening assays
- Enzyme activity assays
- Nuclear receptor screening assays
These assays help you uncover how drugs or substances interact with biological targets, driving forward drug discovery and validation.
Why Tebubio Contract Research Services?
Tebubio provides tailored, high-quality biomarker solutions that give your research a competitive edge. Here’s why researchers trust our lab services:
Save Time
Outsource part or all of your project to Tebubio and focus on advancing your research, while we handle the heavy lifting.
End-to-End Support
From R&D to clinical trial projects, our experts are with you at every step, ensuring seamless transitions and reliable outcomes.
Assured Quality
Trust in the accuracy and reliability of your data, with rigorous quality control at every stage of your biomarker study.
Integrative Solutions
Combine biomarker discovery with our in vitro models, providing a holistic approach to your research.
Universal Compatibility
Our platform supports all sample types—from cells and tissues to biological fluids, serum, and plasma.
Human Biological Samples (HBS) Sourcing
Gain access to high-quality human biological samples for your biomarker studies, customized to your project needs.
They trusted us
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Scientific Resources
Read our latest application notes, customer case studies and more.
Multiplex Antibody Array for Protein Profiling and Biostatistical Analysis to
Assess the Effect of Oxaliplatin on Mouse Fibrosarcoma Cell Line
Oxaliplatin’s effects on mouse fibrosarcoma cells were investigated through a multiplex cytokine array targeting 200 cytokines, combined with biostatistical analysis. Differential expression analysis identified 47 significantly altered biomarkers, including MIP-3a, while heatmaps and PCA revealed distinct clustering and expression patterns between treated and untreated cells. GO enrichment analysis further uncovered biological processes and pathways associated with cell death. These results shed light on the molecular mechanisms of oxaliplatin, confirming its role as an ICD inducer and providing a deeper understanding of its impact on immune-related pathways.
Standardized 3D Spheroid Systems Facilitate Drug Screening and Biomarker Identification with High Relevance for Cancer Drug Discovery
This poster delves into the innovative use of standardized 3D spheroid systems to streamline drug screening processes and improve the precision of biomarker identification. By providing physiologically relevant models, these systems offer robust platforms for preclinical research, helping to uncover key insights into therapeutic efficacy and biomarker discovery.
Explore how these cutting-edge tools support advancements in drug development and translational research.
Let's Collaborate to Advance Your Research
Our Biomarker Mapping Platform is designed to bring your research vision to life. Share the details of your project, and a dedicated PhD-level project manager will contact you to explore how we can tailor our solutions to your needs.
FAQ
Find answers to the questions most frequently asked by our users, curated by our experts.
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What are the targets?
Some targets may not be available. A combination of technologies, such as multiplex platforms and ELISA, might be necessary to analyze all the requested biomarkers.
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What are the species?
The choice of species can influence the availability of targets and the compatibility of certain biomarker analysis methods.
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How many samples need to be analyzed?
The number of samples impacts the feasibility of using certain formats, like 96-well plates, which are ideal for large sample sets but may have fewer available targets.
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How many replicate tests are required?
Replicates are critical for data reliability, especially when working with multiple samples. 96-well plate formats can streamline replicates but come with some target limitations.
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What is the type of sample?
Sample type is essential to determine service pricing, particularly for tissues requiring additional protein extraction steps.
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What is the best strategy: profiling vs. quantification?
For broad exploratory studies, profiling with large biomarker arrays is recommended. For precise analysis, quantification solutions are applied to the profiled biomarkers.
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When should the biostatistics service be offered?
Biostatistical services are particularly relevant for broad exploratory antibody array studies to ensure data is interpreted correctly.