CUTANA™ ChIC/CUT&RUN Kit - 48 Reactions

The CUTANA™ ChIC/CUT&RUN Kit enables streamlined chromatin profiling of histone post-translational modifications (PTMs) and chromatin associated proteins. The CUT&RUN Kit Version 5 (v5) now includes an additional control antibody (H3K27me3). Positive (H3K4me3 and H3K27me3) and negative (IgG) control antibodies pair with SNAP-CUTANA™ spike-in controls for assay optimization and continuous assay monitoring (Figure 2). E. coli DNA is included for data normalization. SPRI magnetic beads are used for DNA purification, enabling seamless multi-channel pipetting throughout the workflow to maximize throughput and reproducibility. The kit is compatible with a variety of inputs including cells or nuclei derived from native, cryopreserved, or cross-linked samples. While it is recommended to start with 500,000 cells, comparable data can be generated using as few as 5,000 cells. The inclusion of controls, as well as compatibility with diverse target types, sample inputs, and low cell numbers, make t