9-plex Human MLH1 Methylation Profile Suite Suite - 4 boxes

The 9-plex PCR-ready assay is specifically designed to target methylation profiling of the MLH1 gene and its associated regulatory regions. This panel covers key functional areas, including 5'-upstream regions, 5'-UTR, exon 1, and multiple introns, with a total of 9 assays and 46 CpG sites. It also integrates functional annotations linked to enhancers and promoters, as referenced by Encode database accession numbers, making it a robust tool for epigenetic research and gene regulation studies. Functional Regions Covered: 1. 5'-Upstream (ADS8979, ADS8976, ADS5187, ADS5188B): Includes distal and proximal enhancers with Encode Accession#: EH38E2192183, EH38E2192187, and EH38E2192189. 2. 5'-UTR and Exon 1 (ADS5188B, ADS8985): Overlaps with CGI 93 and promoter regions critical for MLH1 regulation. 3. Introns (ADS8989, ADS8990, ASY3463, ADS8992): Includes intron 1, intron 2, and intron 9, associated with proximal enhancer functions (EH38E2192192, EH38E2192193). Notable Features: The panel