Accelerate Drug Screening with Personalized in vitro Models
As a trusted Contract Research Services Laboratory, Tebubio provides a complete, personalized service to support your in vitro modeling research studies.
From standardized tests to fully customized projects, we guide you through every step, from the choice of model to your readout of choice.
Your research project is managed by a dedicated PhD-level expert, ensuring that your work is not only in good hands but optimized for success.
Cell-Based Assays
Cell-based assays are essential tools in life science and drug discovery research, providing insights into gene, protein, or cellular functions and their regulatory mechanisms.
These assays evaluate the quality and function of cellular products by measuring their response in a controlled in vitro model. They enable researchers to screen for potential molecules or compounds affecting biological processes or to localise an effect or event within the cell. A cell-based assay can either be based on isolated primary cells or performed on cell lines, from setups as simple as 2D layers of adherent monocultures to complex 3D multicellular assays.
Common applications include cell viability, proliferation, apoptosis, or necrosis assays, ROS actvity assays, ADCC/ADCP assays, migration assays, etc.
3D Models for Drug Screening
Step into the future of drug discovery with Tebubio's 3D in vitro models such as spheroids and tumoroids to recapitulate the tumor formation and microenvironment as close as in vivo models to study the effect of your anticancer drugs on their growth and cell survival.
These predictive systems bridge the gap between research and real-world results, empowering your studies with precision. Indeed, those models permit the creation of disease environments such as tumor microenvironments or inflammatory responses, providing insights into how therapies interact with diseased tissues.
Whether you're evaluating efficacy, toxicity, or both, our tailored 3D systems provide the robust insights you need to accelerate your drug development pipeline.
Models developped in the lab include CRC spheroids made from HCT116 cells, Breast cancer spheroids made from MCF-7 and fibroblasts, Breast cancer tumoroids made from breast tumor DTCs (derived tumor cells).
Organ-On-Chip: A Revolution in Research
Push the boundaries of in vitro modeling with organ-on-chip technologies, a cutting-edge solution that replicates the microphysiological environments of human organs.
For example, models of blood-brain barrier on microfluidic chips allow researchers to study barrier permeability and transport mechanisms.
This innovative approach offers unmatched insights into organ-level responses, helping reduce reliance on animal models and achieve higher predictive accuracy for human outcomes.
Disease Modeling: Replicating Human Pathologies
Our disease modeling platform allows researchers to mimic the complex biology of human diseases, enabling preclinical evaluation of treatments in a controlled in vitro setting.
Models aim to recapitulate the development and treatment of diseases in a dish as 2D or 3D models using differentiated cells or organoids derived from healthy and patients’ cells.
These models are designed to deliver predictive, human-relevant data, offering a powerful tool for drug discovery and precision medicine development.
Biobanking: Securing High-Quality Samples for Research
With Tebubio's biobanking solutions, researchers gain access to a repository of well-characterized biological samples essential for generating reproducible and meaningful data.
Our service ensures the careful handling, temporary storage, quality controls, and transportation to your facility of samples such as primary cells, tissues, and organoids, preserving their integrity over time.
By utilizing these samples, you can accelerate your research projects while benefiting from highly standardized and ethically sourced materials.
Custom 2D/3D Modeling Development
Every project is unique, and our custom 2D/3D modeling service is designed to address your specific research challenges.
From establishing tailored disease models to replicating complex tissue environments, we collaborate closely with you to design bespoke experimental setups.
Whether you're working on tumor invasion studies or compound screening in specific models, our experts create models that are precisely aligned with your scientific objectives and help you uncover actionable results.
Projects developed in the lab include cell line engineering, skin explants culture, scratch assay, fresh pancreatic islets culture, protein production, etc.
Why Tebubio Contract Research Services?
Discover how Tebubio’s innovative in vitro models and expert support empower your research. From predictive drug screening to personalized project management, we provide tailored solutions to ensure your success.
Diverse Cellular Models for Tailored Research
Gain easy access to a wide variety of cellular models, including cell lines, primary cells, and iPSC & stem cells, designed to suit your specific research needs.
Whether you’re exploring standard cell models or advanced regenerative biology applications, our platform ensures you have the right tools to advance your scientific goals.
Wide Range of in vitro Testing Capabilities
At Tebubio, we offer cutting-edge testing solutions using cell biology, microscopy, and microfluidic platforms.
From drug screening to toxicity assessments, our tools and expertise ensure precise, reliable results to advance your research.
Customizable Readouts for Precise Insights
Harness the power of fully customizable readouts, made possible through the seamless collaboration between Tebubio’s specialized platforms.
By integrating expertise in areas such as cell biology, microscopy, and microfluidics, we tailor analytical outputs to deliver precise, actionable data for your research projects.
Dedicated PhD Project Manager
Your research project will be handled by a dedicated PhD-level expert who guides you every step of the way, ensuring your goals are met efficiently.
They trusted us
Lorem ipsum dolor sit amet, consectetur adipiscing elit. Nullam venenatis tempus ante.
"Quote title"
"Lorem ipsum dolor sit amet, consectetur adipiscing elit. Nullam venenatis tempus ante."
Name | Job position
"Quote title"
"Lorem ipsum dolor sit amet, consectetur adipiscing elit. Nullam venenatis tempus ante."
Name | Job position
"Quote title"
"Lorem ipsum dolor sit amet, consectetur adipiscing elit. Nullam venenatis tempus ante."
Name | Job position
Scientific Resources
Read our latest application notes, customer case studies and more.
Development of Cost Effective and Robust 3D Colorectal Cancer Models for Physiological Drug Response Analysis
Our customer needed to obtain in vivo like responses to drug treatment, through monitoring parameters such as gene expression, biomarker analysis, cellular viability, invasion capability.
Discover how robust and cost-effective 3D colateral cancer models replicate physiological drug responses.
This poster showcases innovative platforms for preclinical research and drug development.
Standardized 3D Spheroid Systems Facilitate Drug Screening and Biomarker Identification with High Relevance for Cancer Drug Discovery
This poster delves into the innovative use of standardized 3D spheroid systems to streamline drug screening processes and improve the precision of biomarker identification. By providing physiologically relevant models, these systems offer robust platforms for preclinical research, helping to uncover key insights into therapeutic efficacy and biomarker discovery.
Explore how these cutting-edge tools support advancements in drug development and translational research.
Let’s Collaborate to Advance Your Research
Our in vitro platform is designed to bring your research vision to life. Share the details of your project, and a dedicated PhD-level project manager will contact you to explore how we can tailor our solutions to your needs.
FAQ
Find answers to the questions most frequently asked by our users, curated by our experts.
-
Can I send you my cells?
Yes, you can as long as they do not require more than a BSL-2 biosafety level. Your cells can arrive either in culture or frozen in dry ice. Your cells will be tested for mycoplasma upon their arrival/thawing at Tebubio's facility.
-
Can you send me the cells already plated?
Yes, we can. The feasibility of this delivery will be evaluated with you during your project discussions.
-
Can you source the cells necessary for my in vitro model study?
Yes, we can as long as their use at Tebubio is compliant with their licensing restrictions. Tebubio has a network of suppliers that allows us to buy a broad variety of cells (commercial and primary cells lines, patients’ derived cells).
-
What safety levels for our compounds and samples do you accept?
We accept most compounds and samples with a biosafety of BSL-1 and BSL-2. Of note, we do not accept replicative viruses. A biological and chemical risk assessment will be required before sending your samples and compounds to Tebubio.
-
I have a specific protocol that I would like to follow, can you do that?
Yes, we can. The feasibility of this protocol will be evaluated with you during your project discussions.
-
I have no idea what protocol to follow for my specific in vitro model, can you help?
Yes, we can. At Tebubio, CRS team and SST work together to help design a feasible protocol tuned for your specific needs.