Chemicals & Small Molecules

S-(5'-Adenosyl)-L-methionine solution. Useful as a methionine donor in methyltransferase assays.

The fluorogenic PDE substrate FAM-cAMP is used for cAMP-dependent phosphodiesterase assays. It has been used in activity assays for PDE1, PDE2, PDE3, PDE4, PDE7, PDE8, PDE10 and PDE11.

The fluorogenic PDE substrate FAM-cGMP is used for cGMP-dependent phosphodiesterase assays. It has been used in activity assays for PDE5, PDE6 and PDE9.

The Terbium Donor, also known as Tb Donor, is used for phosphodiesterase (PDE) TR-FRET (Time Resolved Fluorescence Resonance Energy Transfer) technology based assays including PDE1B, PDE1C, PDE3A, PDE4D, and PDE10A. In these assays, terbium conjugates with phosphate.

N-formylkynurenine (Kyn) is an intermediate in the catabolism of tryptophan by enzymes such as indolamine 2,3-dioxygenases (IDO1 & IDO2) and tryptophan 2,3-dioxygenase (TDO). It is a formylated derivative of kynurenine and exhibits an absorption peak at ? = 321 nm.

GC376 a 3CL protease inhibitor is optimized for use with the 3CL Protease (SARS-CoV-2) Assay Kit (BPS Bioscience #79955) and 3CL Protease (SARS-CoV) Assay Kit (BPS Bioscience #78015).

Suitable for Kinase-Glo and ADP-Glo detection and for use with select BPS Bioscience Kinase Assay Kits.

Carbidopa is a decarboxylase inhibitor used in conjunction with levodopa in patients with Parkinson's disease. Carbidopa inhibits the peripheral metabolism of levodopa, which allows a greater proportion of the levodopa to cross the blood - brain barrier for central nervous system effects,

Levodopa is a dopamine precursor that is being studied as a potential treatment for the symptoms of Parkinson's disease. Levodopa crosses the blood brain barrier where it is converted to dopamine by DOPA decarboxylase.