Chemicals & Small Molecules

Phenylmethyl N-(10-bromodecyl)carbamate

BP Fluor 488-PEG-CH2COOH, MW 2,000 possesses BP Fluor 488, which is a popular labeling dye used in Click Chemistry reactions. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The carboxylic handle can be further derivatized or conjugated with amines in the presence of HATU. The conjugates are widely used in microscopy, flow cytometry, and other applications.

Fmoc-Gly-OH

H-Ile-Gly-OH

BP Lipid 406 is an analog of LP01 featuring an ionizable azetidine head group. This heterocyclic functionality was designed to fine-tune the properties of this popular lipid while maintaining the unsaturated and branched lipid tails, and the biodegradable ester and carbonate linkages. This compound may be used as a novel component in lipid nanoparticle (LNP) formulations. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Mal-C5-Val-Ala-PAB-MMAE is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. Maleimide (Mal) group is reactive toward thiol groups.

Acid-PEG1-NHS ester is a PEG linker containing a carboxylic acid and an NHS ester. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU). The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Bis-sulfone-PEG1-Bis-sulfone is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact.

Gly-Gly-Gly-PEG7-methyltetrazine is a tripeptide featuring three glycine residues. The methyltetrazine can react with TCO-containing compounds without the catalysis of Cu or elevated temperatures. The PEG7 spacer imparts aqueous solubility of the compound.