Chemicals & Small Molecules

Exatecan-2-(aminomethoxy)acetamide-Gly-Phe-Gly-Gly-acid serves as a tetrapeptide linker-payload conjugate that may be employed in the creation of antibody drug conjugates (ADCs). Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

TCO-PEG3-PB is a click chemistry fluorescent dye containing a tetrazine-reactive TCO moiety and pacific blue moiety which has an excitation wavelength of 410 nm and emission maxima of 455 nm.

DSPE-Hyd-PEG-MAL, MW 2,000 constitutes a phospholipid polyPEG with a hydrazone moiety, which can self-assemble to form a lipid bilayer in aqueous solution. The polymer can be used to prepare liposomes as a drug delivery vehicle. Hydrazone linkages are useful for coupling drugs to targeted antibodies where the linkage is stable at neutral pH, but is rapidly destroyed in the acidic environment of lysosomes of the cell. The maleimide moiety can react with cysteine or other thiol-bearing molecules for bioconjugation. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Exatecan-2-(aminomethoxy)acetamide-Gly-Phe-Gly-Gly-PEG1-NHS ester functions as linker-payload conjugate featuring an NHS ester which can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Exatecan-2-(aminomethoxy)acetamide-Gly may be employed as a payload in ADC research. The peptide linker is a cleavable linker that may be useful for drug delivery. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Bz-rA Phosphoramidite represents a TBDMS-protected nucleoside phosphoramidite, which can be used to create oligonucleotides. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azide-PEG8-Val-Cit-PABC-Exatecan is a unique linker payload containing an azide handle for Copper-Catalyzed click chemistry with alkyne, DBCO, and BCN. The PEG8 chain improves hydrophilicity and helps fine-tune DMPK properties. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

A fully saturated lipid featuring two biodegradable ester linkages to branched lipid tails. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Fluorescein-PEG8-Acid is a xanthene dye with excitation/emission maximum of 494/517 nm and a free terminal carboxyl acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. It could be used as a quantum yield standard. Hydrophilic PEG spacer increases solubility in aqueous media and reduces steric hindrance during binding. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Lipid 425 is a symmetric polar lipid featuring a two unsaturated oleic acid tails and useful maleimide-PEG4 linker. This compound may be used for bioconjugation and surface modification applications, or as a useful synthetic scaffold for novel lipids. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.