Chemicals & Small Molecules

Astrophloxine is a fluorescent dye which acts as a positively charged probe to resolve cholesterol in solution on cell membranes observed towards the spectral short-wave region. Studies suggest that Astrophloxine is beneficial in identifying the changes in the microenvironment surrounding the cell membrane. Furthermore, Astrophloxine in conjunction with microelectrophoresis can be used to research hypercholesterinemia, atherosclerosis, and D-hypovitaminosis in vitro by using the positively charge probe as a ligand to identify the compounds of interest.

An optical chemical species used in the preparation of samples for spectroscopic analysis. It is a general purpose laser that can be activated by a variety of wavelengths including radiation from the cavity or light emission. The sample cell is filled with a solution of [[(4-(tert butyl)-3,5-(dimethyl))pyrrolo[2,1,1]-benzoxazin] (DFB), which emits fluorescence upon excitation. Fluorescence lifetimes are measured using an energy efficient laser and solid phase microextraction. Optimum concentrations for DFB are about 0.05%.

Coumarin 314 is a dye which has an intense absorption in the visible and additionally presents a large solvent dependence. Coumarin 314 is a naturally occurring coumarin derivative with a wide range of biological activities. It was first isolated from the leaves of the plant, Cinnamomum cassia, and has been widely studied for its potential therapeutic applications. Coumarin 314 has been shown to possess anti-inflammatory, antioxidant, and anti-cancer properties and is being investigated for its potential use in a variety of biological processes.

Coumarin 30, also known as 3,4-methylenedioxy-coumarin, is a naturally-occurring phenolic compound found in various plants, including tonka beans, lavender, and cinnamon. It is widely used in the industrial, medical, and food industries due to its unique properties and applications.

2,7′-Dichlorofluorescein Sodium Salt (DCF) is a fluorescent dye that finds extensive application in diverse scientific research endeavors. It serves as a valuable tool for researchers due to its versatile nature, enabling the detection of reactive oxygen species (ROS), exploration of enzyme activity, and analysis of cell signaling pathways. Moreover, DCF proves instrumental in numerous laboratory experiments, encompassing cell culture, protein purification, and bioassays. The utilization of 2′,7′-Dichlorofluorescein Sodium Salt spans a wide array of scientific research applications. It plays a pivotal role in ROS detection, study of enzyme activity, and analysis of cell signaling pathways. Additionally, 2′,7′-Dichlorofluorescein Sodium Salt serves as a valuable tool for detecting DNA damage, studying apoptosis, and quantifying intracellular calcium levels. As a fluorophore, 2′,7′-Dichlorofluorescein Sodium Salt absorbs light and emits light at a distinct wavelength. Upon light exposure

7-(dimethylamino)coumarin-3-carboxylic acid is utilized as a laser dye, fluorescent label, and biomedical inhibitor in various applications.

Dansyl fluoride is a fluorogenic reagent used as a specific fluorescent probe for serine proteases and is a serine-type protease inhibitor. It is an active site directed fluorescent inhibitor of guanidinobenzoatase (GB), which binds to both the colonic isoenzymic forms of the GB. The GB on cell surfaces after binding dansyl fluoride makes the cells fluoresce blue. It has been used for the location of tumour cells in frozen sections of human lung squamous cell carcinoma and colonic carcinoma tissues. It is used as a precursor for the synthesis of other derivatives like dansyl amide. Spectral data: λex 360nm; λem 580nm (methanol).

3,3'-Dipropylthiadicarbocyanine iodide is applied for transmembrane potential measurements.

3,3′-Diethyloxadicarbocyanine iodide is a suitable dye for mode-locking both pulsed and cw tunable rhodamine 6G lasers. It has been used as a micellar probe as it is positively charged and it stays at the micelle–water interface.