Chemicals & Small Molecules

7-(Diethylamino)-4-(trifluoromethyl)coumarin is a fluorinated heterocyclic compound with a diethylamine (7-position) and a trifluoromethyl (4-position) substituents. As a coumarin derivative, 7-(Diethylamino)-4-(trifluoromethyl)coumarin is commonly applied as dyes with excellent light conversion capability with quantum yield of 94.8%. It is a promising candidate to be applied in OLEDs and dye-sensitized solar cells (DSSCs). 7-(Diethylamino)-4-(trifluoromethyl)coumarin can be modified with Lawesson's reagent to thiocoumarin. The modification allows further functionalization to the molecules resulting shifts in the absorption and emission spectra. The emission of the coumarin derivatives ranges from 380 nm to 550 nm, which is ideal for bioimaging.

Ethyl 7-(diethylamino)coumarin-3-carboxylate is a reactive molecule that has been used in photochemical reactions to produce molecules with fluorophores. The active methylene group in the molecule reacts with chlorine atoms to form an intermediate that reacts with other intermediate molecules to form the desired product. This compound is not stable and cannot be stored for long periods of time. It can be synthesized from coumarin derivatives, which are compounds derived from aromatic hydrocarbons. Ethyl 7-(diethylamino)coumarin-3-carboxylate has been used as a fluorophore in the synthesis of other compounds due to its fluorescence properties. Hydrogen bonds play an important role in stabilizing this compound and intramolecular hydrogen bonding occurs between the carbonyl oxygen and the amide nitrogen atom. Desulfurization also takes place during synthesis, which makes it more reactive by removing sulfur atoms and

Pyrromethene 567 - used to generate fluorescent conjugates of proteins; nucleotides; oligonucleotides and dextrans; and to prepare fluorescent enzyme substrates; fatty acids; phospholipids; lipopolysaccharides; receptor ligands and polystyrene microspheres.

Stains living cells green. Substrate for esterases. Suitable for use in cell viability assays. Removal of the acetate groups by cellular esterases results in fluorescence in cells with intact membranes.

Intermediate to forming more complex fluorescein/rhodamine derivatives? No other information found online

2,7′-Dichlorofluorescein ) is a fluorescent dye that finds extensive application in diverse scientific research endeavors. It serves as a valuable tool for researchers due to its versatile nature, enabling the detection of reactive oxygen species (ROS), exploration of enzyme activity, and analysis of cell signaling pathways. Moreover, DCF proves instrumental in numerous laboratory experiments, encompassing cell culture, protein purification, and bioassays. The utilization of 2′,7′-Dichlorofluorescein spans a wide array of scientific research applications. It plays a pivotal role in ROS detection, study of enzyme activity, and analysis of cell signaling pathways. Additionally, 2′,7′-Dichlorofluorescein serves as a valuable tool for detecting DNA damage, studying apoptosis, and quantifying intracellular calcium levels. Upon light exposure, it emits a vibrant orange-red fluorescence, facilitating the identification of ROS and other molecules within cells. Moreover, it enables the detectio

AMCA-PEG4-NHS ester is a AMCA dye linker containing a NHS ester group and a hydrophilic PEG spacer arm. The NHS ester allows the dye to react with primary amines and the hydrophilic PEG spacer arm increases water solubility as well as membrane permability. This dye is used for protein and peptide labeing. The structure is similar to commercial AMCA-X-SE with better solubility and conjugation efficiency. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Fluor 546 Alkyne is a bright, orange-fluorescent dye that reacts with terminal azide via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker. It is a popular labeling dye used in Click Chemistry reactions. BP Fluor 546 Alkyne is a water-soluble, pH-insensitive (from pH 4-10), orange-fluorescent dye with absorption and emission maxima at 554 and 570 nm, respectively. It can be used with the 488 nm and 532 nm laser lines. BP Fluor 546 conjugates to a variety of antibodies, peptides, proteins, tracers, and amplification substrates which are often used for generating stable signals in imaging and flow cytometry. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

9-azido-9-deoxy-N-acetylneuraminic acid (9AzNeu5Ac), a Neu5Ac analogue with the substitution of 9-hydroxyl group with an azide, is a great click chemistry reagent could be metabolized and incorporated into sialoglycans in living cells and mice. It will react with the DBCO or other alkyne group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. Metabolic labeling of glycans with unnatural sialic acid analogues has emerged as an invaluable tool for studying sialic acid biology. The incorporated sialic acid analogue, 9AzNeu5Ac, enable visualization the cell-surface sialoglycans and glycoproteomic profiling by click-labeling with fluorophores and affinity tags, respectively. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.