Chemicals & Small Molecules

Chondroitin sulfate sodium (Chondroitin polysulfate sodium) is a naturally occurring glycosaminoglycan extracted from animal cartilage that is used as a food supplement with antitumor activity, reduces inflammatory mediators and apoptotic processes, and decreases the production of inflammatory cytokines, iNOS, and MMPs, and may be used in the study of Osteoarthritis.

6-O-Propynyl-2'-deoxyguanosine, a click chemistry reagent with an alkyne group, facilitates research in various biochemical [1] contexts.

Didocosanoin, a diacylglycerol, incorporates the saturated 22-carbon fatty acid, docosanoic acid, at both of its positions.

trans-Petroselinic Acid (Δ6-trans-Octadecenoic Acid) is a trans-isomer of fucoidan and an isomer of oleic acid, which can be extracted from milk fat of cows, goats and ewes, as well as human breast milk.

2,7-Dichlorodihydrofluorescein (DCFH2) serves as a non-fluorescent probe, which becomes the highly fluorescent 2′,7′-dichlorofluorescein (DCF) for detecting reactive oxygen species [1] [2].

5-Sulfosalicylic acid, a sulfonated salicylic acid derivative, is effective against breast cancer cell lines with less toxicity [1] and possesses antioxidant activities [2].

800CW NHS ester is a near-infrared probe used for labeling lysine residues (λ max = 776 nm) [1][2].

Ac4ManNDAz serves as a cell-permeable photocross-linking probe that competes effectively with endogenous sialic acid to incorporate into cell surface glycoproteins. Upon exposure to UV light, it forms cross-links with glycoprotein ligands. This compound is particularly useful for studying interactions between glycoproteins [1].

ACBI3 is a selective pan-KRAS degrader with anticancer activity that degrades oncogenic KRAS. ACBI3 inhibits the growth of most cancer cell lines driven by KRAS mutations.