Activators & Inhibitors

FL118-14-Propanol is a cytotoxic camptothecin derivative, a potential topoisomerase I inhibitor with potential antitumor activity, which can be used in the synthesis of ADC compounds.

Mandipropamid is an agrochemical inducer that specifically induces complex formation between hexameric mutants of the phytohormone receptor pyrabactin-resistant 1 (PYR1) and abscisic acid insensitive (ABI).

Red-HyP-1 is a red dye that can be used for in vivo hypoxia imaging. The maximum emission maximum of Red-HyP-1 is 798 nm.

S-Y048 is an Oxoeicosanoid (OXE) receptor antagonist that inhibits allergen-induced eosinophil infiltration into the skin of experimentally sensitized rhesus monkeys to house dust mites and inhibits lung inflammation caused by aerosolized allergen challenge. S-Y048 can be used to study asthma and other eosinophilic diseases.

NT-0249 is an orally active inhibitor of the inflammatory vesicle NLRP3 with anti-inflammatory activity that reverses high-fat diet-induced obesity, systemic inflammation, and astrocyte hyperplasia.

4-Di-2-ASP, a styryl pyridinium fluorescent dye, serves as an essential mitochondrial marker. It effectively and specifically labels pulmonary NEBs (neuroepithelial bodies) [1].

AF647-NHS ester, an analogue of Alexa Fluor 647 (AF647), is a bright, far-red fluorescent dye [1]. Storage: protect from light.