Nucleotides

N4-Bz-3'-O-(4,4'-dimethoxy trityl)-2'-O-(2-MOE)-5-methylcytidine-5'-CED phosphoramidite, including a 2'-O-MOE group, can be integrated into oligonucleotide phosphoramidites for making antisense RNA. The 2'-MOE backbone improves duplex stability, nuclease resistance, and has low toxicity.

N-DMTr-N2-isobutyryl-morpholino-G-5’-O-phosphoramidite is a synthetic molecule that is the product of a redesign of natural nucleic acid structures where methylenemorpholine rings are linked through phosphorodiamidate groups instead of phosphates. Reagent grade, for research purpose.

N-DMTr-N6-benzoyl-morpholino-A-5’-O-phosphoramidite is a synthetic molecule that is the product of a redesign of natural nucleic acid structures where methylenemorpholine rings are linked through phosphorodiamidate groups instead of phosphates. Reagent grade, for research purpose.

N-DMTr-N4-benzoyl-morpholino-cytosine-5’-O-phosphoramidite is a synthetic molecule that is the product of a redesign of natural nucleic acid structures where methylenemorpholine rings linked are through phosphorodiamidate groups instead of phosphates. Reagent grade, for research purpose.

N-DMTr-morpholino-T-5’-O-phosphoramidite is a synthetic molecule that is the product of a redesign of natural nucleic acid structures where methylenemorpholine rings are linked through phosphorodiamidate groups instead of phosphates. Reagent grade, for research purpose.

N-DMTr-morpholino-U-5’-O-phosphoramidite is a synthetic molecule that is the product of a redesign of natural nucleic acid structure where methylenemorpholine rings are linked through phosphorodiamidate groups instead of phosphates. Reagent grade, for research purpose.

DMTr-MOE-Inosine-3-CED-phosphoramidite introduces a MOE-modified inosine nucleoside for antisense RNA synthesis, enhancing duplex stability and nuclease resistance through its MOE backbone.

DMTr-LNA-C(Bz)-3-CED-phosphoramidite is a Locked Nucleic Acid (LNA) building block, crucial for LNA oligonucleotide synthesis. It features a ribonucleoside linked via a methylene unit between the 2’-oxygen and 4’-carbon atoms in a bicyclic structure.

DMTr-dH2U-amidite is a uracil phosphoramidite monomer which can be modified in order to create oligonucleotides.