Nucleotides

8-Bromoadenosine is a nucleotide that is structurally related to adenosine. It can be used as an inhibitor of guanine nucleotide-binding proteins and has shown biological properties in vitro. 8-Bromoadenosine has been shown to inhibit the mitochondrial membrane potential, cytosolic Ca2+, and the synthesis of RNA and protein. 8-Bromoadenosine also inhibits leukemia inhibitory factor (LIF) production by 3T3-L1 preadipocytes and induces apoptosis in T84 cells. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-Benzoyl-2'-deoxyadenosine is a nucleoside analog that is used in the diagnosis of infections caused by bacteria. N-Benzoyl-2'-deoxyadenosine binds to DNA duplexes and alters their structure, which can be detected using electrophoresis. N-Benzoyl-2'-deoxyadenosine has been shown to have low bioavailability and is insoluble in water, so it must be administered intravenously. It has also been found to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-Benzoyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine is a novel nucleoside analog that is structurally related to the natural nucleotide adenosine. N-Benzoyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine is an activator of ribonucleotide reductase, which converts ribonucleosides to deoxyribonucleosides. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxyadenosine serves as an intermediate in pharmaceutical synthesis.. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-Isobutyryl-5'-O-tert-butyldimethylsilyl-2'-deoxyguanosine can be used to activate proteins, receptors, and ion channels. It has been shown to bind to the receptor site on the cell membrane, which may inhibit the binding of ligands and then initiate signal transduction. N2-Isobutyryl-5'-o-(tert-butyldimethylsilyl)-2'-deoxyguanosine has been shown to inhibit protein interactions, such as antibody binding and peptide binding. This ligand also inhibits the activity of ion channels in a dose-dependent manner. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Adenosine-5'-diphosphate disodium salt is a sodium salt of adenosine 5'-diphosphate. Adenosine 5'-diphosphate disodium salt has been shown to inhibit the binding of serotonin (5-hydroxytryptamine) to 5-HT2 receptors, which are present in heart tissue. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Adenosine-5'-monophosphoric acid is a nucleotide that is synthesized from adenosine triphosphate and inosine monophosphate. Adenosine-5'-monophosphoric acid is an important molecule in the body because it is a substrate for cyclic AMP, which regulates many cellular processes. Adenosine-5'-monophosphoric acid also has biochemical properties that are similar to those of the neurotransmitter serotonin and it can activate the 5-HT2 receptors. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Adenosine-5'-triphosphate disodium salt hydrate is used for the detection of fatty acids, caffeine, and chemiluminescent assays. Adenosine 5'-triphosphate disodium salt hydrate can be used to measure the hydration level of cells by using a chemiluminescent assay. Adenosine 5'-triphosphate disodium salt hydrate has also been shown to promote pro-inflammatory cytokines such as IL-6 and IL-8 secretion from macrophages. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.