Chemicals & Small Molecules

4-Hydroxycyclohexanecarboxylic acid is a substrate of cyclohexanecarboxylic acid and is isolated from olive brine.

FAPy-adenine HCl is a metabolic marker for Attention Deficit Hyperactivity Syndrome and is a mutagenic product of ROS-induced DNA damage.

N,N-Dicyclohexylcarbodiimide (Dicyclohexylcarbodiimide) is a cross-linking agent involved in the production of hydrogel compounds for the synthesis of active ester-containing reagents.

Sulfamethoxazole-NO (SMX-NO) is a SMX-NO derivative that is a major immunogen for sulfonamide hypersensitivity reactions, is cytotoxic, and is immunogenic in rodents.

Tri(2-butoxyethyl) phosphate (Phosflex T-bep), a plastic plasticizer and flame retardant, is an organophosphate derived from milk powder.

Protein acetylation is a common posttranslational modification that plays a crucial role in regulating biological processes such as gene expression, cell proliferation, and metabolic regulation. The acetylation level of proteins within cells is regulated by both acetyltransferases and deacetylases. Deacetylase inhibitors can effectively prevent the loss of acetylation modifications to increase the acetylation level. TargetMol deacetylase inhibitor cocktail consists of four components that effectively inhibit the activity of various deacetylases and maintain protein acetylation status, including reversible inhibitors for Class I/II deacetylases such as Trichostatin A and Sodium Butyrate, a reversible inhibitor for Class III deacetylases (sirtuins, SIRTs) like Nicotinamide, and a selective reversible inhibitor for SIRT1, known as EX-527. To enhance the detection of protein acetylation level, deacetylase inhibitor cocktail can be added to cell culture medium for a certain incubation perio

Penicillin-streptomycin solution, also known as Pen-Strep, is the most commonly used combined antibiotic solution against both gram-positive and gram-negative bacteria. Penicillin can directly interfere with the synthesis of bacterial cell wall and indirectly alter the cell wall by triggering enzymatic reactions. Streptomycin can bind to the 30S subunit of the bacterial ribosome, and inhibit the synthesis of bacterial protein, ultimately leading to the death of susceptible bacteria. The solution is used to supplement cell culture media to control bacterial contamination. TargetMol's penicillin streptomycin solution (100x) is a sterile, filtered and ready-to-use antibiotic solution for cell culture. This solution contains 10,000 units/mL of penicillin and 10 mg/mL of streptomycin, prepared in 0.9% NaCI. It is recommended for use in cell culture application at 100 units/mL of penicillin and 0.1 mg/mL of streptomycin. Dilute the product 100-fold for use.

Penicillin-streptomycin-amphotericin B solution, is a commonly used solution to reduce bacterial and fungal contamination in cell culture media. Penicillin can directly interfere with the synthesis of bacterial cell wall and indirectly alter the cell wall by triggering enzymatic reactions. Streptomycin can bind to the 30S subunit of the bacterial ribosomal and inhibit the synthesis of bacterial protein, ultimately leading to the death of susceptible bacteria. The combination of penicillin and streptomycin exhibits effective antibacterial activity against both gram-positive and gram-negative bacteria. Amphotericin B exerts its antifungal effect by binding to ergosterol on the bacterial cell membrane, which will damage membrane, lead to the increase of permeability, leakage of intracellular substances and the disruption of normal metabolism. TargetMol's penicillin-streptomycin-amphotericin B solution (100×) is a sterile, filtered and ready-to-use solution for cell culture. This solution

Gentamicin solution, is a broad-spectrum aminoglycoside antibiotic that remains stable under heat and pH variations. The solution is effective against a wide range of Gram-negative and Gram-positive bacteria and is commonly used to prevent the contamination of cell cultures by bacteria. Gentamicin exerts its antibactericidal effect by irreversibly binding to the 30S subunit of the bacterial ribosome, inhibiting bacterial protein synthesis and disrupting the integrity of the bacterial cell membrane. TargetMol's gentamicin solution is a sterile, filtered and ready-to-use solution for cell culture, containing 10 mg/mL of gentamicin sulfate. It is recommended for use in cell culture application at 0.5-50 μg/mL of gentamicin. Dilute the solution as experimental needs.