Please note this product may be subject to fees, we invite you to contact your local office. The CFTR HEK293 Cell Line expresses full length, wild-type human cystic fibrosis transmembrane conductance regulator (CFTR) protein (Genbank #P13569, NP_000483.3), with a C-terminal Streptavidin-Binding Peptide (SBP) tag. Expression must be induced ≥24 hours prior to an experiment using 1 µg/ml Doxycycline and 3 mM Na-butyrate. The inducible expression of CFTR was confirmed by Western blotting and flow cytometry.

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant CHOK1 cell line expressing Human sodium-dependent dopamine transporter (DAT), Genbank accession number NM_001044

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant HEK293 cell transfected with empty expression vector containing the neomycin resistance gene. This cell line serves as a negative control for<br> • TMEM16A-HEK293 Cell Line Cat. #90230<br> • TRPC3-HEK293 Cell Line Cat. #90130<br> • TRPC7-HEK293 Cell Line Cat. #90030<br> • IKCA1 (KCNN4) - HEK293 Cell Line Cat. #90330<br> • ERG (Kv11.1) - HEK293 Cell Line Cat. #60619<br>

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant clonal stable CHO cell line constitutively expressing full length human folate receptor alpha (FOLR1, also known as FOLR, Genbank #NM_016725.3). Surface expression of FOLR1 was confirmed by flow cytometry.

Please note this product may be subject to fees, we invite you to contact your local office. Human ERG channel has been stably expressed in HEK293 cell line and its expression was confirmed by Western blotting. The channel activity of hERG was characterized by a fluorescence-based assay using thallium influx as a surrogate indicator of potassium ion channel activity coupled with a thallium-sensitive fluorescent dye. When hERG-HEK293 cells were pre-loaded with thallium-sensitive dye and stimulated with stimulus buffer containing potassium/thallium, thallium ions flowed through the open hERG channels into the cells and bound the dye, generating a fluorescent signal. The hERG channel activity in hERG-HEK293 cells was blocked by hERG channel blockers, cisapride or dofetilide, causing the fluorescent signal triggered by thallium influx to drop to the basal level.

Please note this product may be subject to fees, we invite you to contact your local office. Stable, recombinant HEK293 cell line expressing human IKCA1, also known as KCNN4 (Intermediate conductance calcium-activated potassium channel protein 4), IK1, hKCa4, and hSK4, GenBank Accession No. NM_002250.

Please note this product may be subject to fees, we invite you to contact your local office. Stable recombinant HEK293 cell line expressing human Nav1.7 (Genbank # Q15858) fused at the C-terminus to Green Fluorescent Protein [Ex. ~395 nm, 475 nm; em ~510 nm] and with Cterminal Streptavidin-Binding Peptide (SBP) fusion. Nav1.7 is a tetrodotoxin-sensitive voltagegated sodium channel type IX subunit alpha (SCN9A).

Please note this product may be subject to fees, we invite you to contact your local office. Stable recombinant HEK293 cell line expressing tetracycline-inducible human Nav1.8 (Genbank #NP_006505.2) fused to Green Fluorescent Protein (GFP) [Ex. ~395 nm, 475 nm; em ~510 nm] and C-terminal Streptavidin-Binding Peptide (SBP)-tag, and the human sodium channel β2 subunit (Genbank #NM_004588; SCN2B) with C-terminal FLAG-tag. Nav1.8 is also known as tetrodotoxin-resistant voltage-gated sodium channel type X (SCN10A).

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant CHOK1 cell line expressing human norepinephrine transporter (NET), Genbank accession number NM_001043.

Please note this product may be subject to fees, we invite you to contact your local office. Stable recombinant HEK293 cell line expressing human SLC5A5 (UniProt # Q92911) with a C-terminal FLAG- tag. SLC5A5 is a sodium-dependent iodide transporter and is a member of the sodium glucose co-transporter family. The expression of SLC5A5 is confirmed by Western blotting. This cell line can be used to evaluate agents that may affect iodide transport.

Please note this product may be subject to fees, we invite you to contact your local office. Stable, recombinant HEK293 cell line expressing human TMEM16A (transmembrane protein 16A, also called anoctamin 1, calcium-activated chloride channel (ANO1), accession number NM_018043).

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant HEK293 cell line expressing human TMEM16B (transmembrane protein 16B, also called as anoctamin 2, calcium-activated chloride channel (ANO2), accession number NM_001278596).

Please note this product may be subject to fees, we invite you to contact your local office. Stable, recombinant HEK293 cell line expressing human TRPC3 (transient receptor potential cation channel, subfamily C, member 3, accession number NM_003305).

Please note this product may be subject to fees, we invite you to contact your local office. Stable, recombinant HEK293 cell line expressing tetracycline-inducible human TRPM2 (transient receptor potential cation channel, subfamily M, member 2, accession number NM_003307).