Please note this product may be subject to fees, we invite you to contact your local office. The TCF/LEF (T-cell factor/lymphoid enhancing factor) StemBright™ Luciferase Cells contain a firefly luciferase gene under the control of TCF/LEF responsive elements, stably integrated into induced Pluripotent Stem (iPS) cells. TCF/LEF transcription factors are downstream of the Wnt signaling pathway. This cell pool is validated for its response to GSK3β inhibitor CHIR-99021, which activates the Wnt signaling pathway in human pluripotent stem cells.

Please note this product may be subject to fees, we invite you to contact your local office. The StemBright™ Luciferase iPS Cell Pool constitutively expresses the firefly luciferase gene under the control of a CMV promoter, introduced via lentiviral transduction (Firefly Luciferase Lentivirus, BPS Bioscience #79692). Luciferase activity can be used to monitor cell viability, both in vitro and in vivo.