Cell Line

eGFP Daudi Cell Line is a Daudi cell line engineered to express enhanced GFP (eGFP) driven by an EF1a promoter. This cell line was generated by transduction with Enhanced GFP Lentivirus (Puromycin) (BPS Bioscience #78639</a>). This cell line has been validated by flow cytometry for eGFP expression.

HER3 CHO Cell Line is a CHO-K1 cell line expressing HER3 (human epidermal growth factor receptor 3) (NM_001982.2, also known as receptor tyrosine-protein kinase erbB-3) under the control of a cytomegalovirus (CMV) promoter. This cell line was generated by lipid-mediated transfection followed by hygromycin selection and limited dilution. Individual clones were screened for HER3 expression levels by flow cytometry, and a clone was selected to generate this cell line.

The TSLP Responsive Luciferase Reporter Ba/F3 Cell Line is a murine Ba/F3 cell line engineered to express both TSLP-R (thymic stromal lymphopoietin receptor, also known as CRLF2, cytokine receptor like factor 2) (NM_022148.4) and IL-7Ra (Interleukin 7 receptor alpha) (NM_002185.5) separated by a self-cleaving P2A peptide. The construct was delivered bytransduction of STAT5 Luciferase Reporter Ba/F3 cells (#79772</a>), which express a firefly luciferase reporter driven by STAT5 response elements located upstream of the minimal TATA promoter. After activation by TSLP, the endogenous transcription factor STAT5 binds to the response elements, inducing transcription of the luciferase reporter gene. This cell line has been validated to respond to TSLP. Additional functional validation demonstrates that TSLP-induced luciferase activity can be inhibited by either anti-TSLP or anti-TSLPR neutralizing antibodies. TSLP binds to TSLPR, recruits the IL-7Ra co-receptor and activates downstream JAK1/

eGFP/Firefly Luciferase THP-1 Cell Line is a THP-1 cell line expressing firefly luciferase and enhanced GFP (eGFP) driven by an EF1a promoter. The cells were generated by transduction with Firefly Luciferase-eGFP lentivirus (BPS Bioscience #78741), which is a SIN (self-inactivating) lentivirus. Please note this product may be subject to fees, we invite you to contact your local office.

Please note this product may be subject to fees, we invite you to contact your local office.

Please note this product may be subject to fees, we invite you to contact your local office.

Please note this product may be subject to fees, we invite you to contact your local office.

Please note this product may be subject to fees, we invite you to contact your local office.

Please note this product may be subject to fees, we invite you to contact your local office.