Compound Libraries

21 Inhibitors of various immunoregulatory kinases

25 protease inhibitors covering the most common families

10 inhibitors of PI3 kinase isoforms

Broadway Diversity Core Library (Legacy Tebubio ref. 282VM1400). -Most compounds have a molecular weight less than 500, mainly from 250 to 450, facilitating modification and optimization; -Most compounds have a LogP less than 5, indicating favorable solubility. -Hydrogen Bond Acceptor (HBA) and Hydrogen Bond Donor (HBD) counts generally adhere to the Rule of Five (Ro5). -Topological Polar Surface Area (TPSA) ≤110, and the majority of compounds have 10 or fewer rotatable bonds, complying with the Veber’s rule.