Lipids & Polymers

C13-112-tetra-tail is an ionizable lipid molecule containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a PEG2 linker. The lipoid can be formulated into a lipid nanoparticle (LNP) to deliver anionic substrates in vitro and in vivo. This includes siRNA to induce gene silencing in a sequence-specific manner, CAS9 mRNA, and cytotoxic proteins. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

C13-112-tri-tail is an ionizable lipid molecule containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. The lipoid can be formulated into a lipid nanoparticle (LNP) to deliver anionic substrates in vitro and in vivo. This includes siRNA to induce gene silencing in a sequence-specific manner, CAS9 mRNA, and cytotoxic proteins. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

C13-113-tetra tail is an ionizable lipid molecule containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a tertiary amine linker. The lipoid can be formulated into a lipid nanoparticle (LNP) to deliver anionic substrates in vitro and in vivo. This includes siRNA to induce gene silencing in a sequence-specific manner, CAS9 mRNA, and cytotoxic proteins. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

C13-113-tri tail is an ionizable lipid molecule containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a tertiary amine linker. The lipoid can be formulated into a lipid nanoparticle (LNP) to deliver anionic substrates in vitro and in vivo. This includes siRNA to induce gene silencing in a sequence-specific manner, CAS9 mRNA, and cytotoxic proteins. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Tetraethylene glycol is a PEG linker consisting of four ethylene glycol units linked together.

Amino-PEG5-Amine is composed of 5 PEG units with two amino groups. Amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Tos-PEG7-Tos is a PEG linker containing two tosyl groups. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Mal-heptanoic NHS ester contains a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Hydroxy-PEG4-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.