Enzymes

Recombinant human ALK (S1206R) (anaplastic lymphoma kinase), encompassing amino acids 1060-end with a S1206R mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.

Recombinant human ALK (T1151M) (anaplastic lymphoma kinase), encompassing amino acids 1060-end with a T1151M mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.

Recombinant human ALK (T1151 L1152insT) (anaplastic lymphoma kinase), encompassing amino acids 1060-end with the T1151 L1152insT mutations. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.

Recombinant human ALK2 (G328E) (activin receptor-like kinase-2), encompassing amino acids 147-end with a G328E mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.

Recombinant human ALK2 (G328V) (activin receptor-like kinase-2), encompassing amino acids 147-end with a G328V mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.

Recombinant human ALK2 (G328W) (activin receptor-like kinase-2), encompassing amino acids 147-end with a G328W mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.

Recombinant human ALK2 (G356D) (activin receptor-like kinase-2), encompassing amino acids 147-end with a G356D mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.

GenCRISPR™ LbuCas13a Nuclease is an RNA-guided RNA endonuclease from Leptotrichia buccalis. Cas13a (previously known as C2c2) belongs to the Class 2 Type VI CRISPR-Cas system and contains a single protein effector with two HEPN domains. Cas13a exhibits two distinct ribonuclease activities. Cas13a possesses sequence-specific RNA cleavage activity in vitro and in vivo. And after specific cleavage, Cas13a activates collateral cleavage activity towards adjacent non-specific ssRNA sequences. The two distinct ribonuclease activities of Cas13a enable guide-RNA processing and RNA detection. The RNA detection empowered with Cas13a-crRNA complex and quenched fluorescent ssRNA as reporter has been reported to be versatile, rapid and high-specific.

Human CD52 full-length ORF (AAH00644.1, 1 a.a. - 61 a.a.) recombinant protein with GST tag at N-terminal.