Labelling

Fluorescein-PEG12-(N-Boc)-Amine is a heterobiofunctional PEG linker containing a fluorescein dye and a Boc-protected amine group, which can be regenerated by mild acidic conditions and then be reactive with cabroxylic acid, activated NHS ester, carbonyl (ketone, aldehyde) etc. Fluorescein is a common fluorescent tracer (494nm/521nm) for staining cells, tissues, biomarkers or nanoparticles and this reagent can be used to tag biomolecules and nanoparticles. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Sulfo DBCO-UBQ-2 is a click chemistry reagent combining a dark quencher, UBQ-2, with a polyaromatic-azo backbone, offering no native emission. It effectively quenches fluorescence in the 560-670 nm range, ideal for qPCR probes and FRET applications with orange to far-red dyes. The DBCO group participates in copper-free click chemistry, while the sulfo group enhances water solubility.

UBQ-1 is a dark quencher with a polyaromatic-azo backbone, exhibiting no native emission. It quenches fluorescence in the 480-580 nm range, making it ideal for qPCR probes and FRET applications with green to yellow dyes like FAM, Oregon Green®, TET, JOE, HEX, Alexa Fluor® 488, and DyLight® 488.

Sulfo DBCO-UBQ-1 serves as a click chemistry reagent uniting UBQ-1, which is a dark quencher with a polyaromatic-azo backbone that exhibits no native emission, with a sulfo group for improved hydrophilicity and DBCO for undergoing copper-free click chemistry.

(+)-JQ-1-PEG4-Amine, TFA salt features an amino (NH2) group reactive with activated NHS esters or carboxylic acids in the presence of EDC or HATU. It includes (+)-JQ-1, a potent, specific, and reversible pan-BET family inhibitor useful for studying BET bromodomains in oncogenesis. The PEG4 linker adds water solubility to the compound.

Fluorescein-PEG4-DBCO is a xanthene dye containing a reactive DBCO group and a hydrophilic PEG spacer arm with excitation/emission maximum of 494/517 nm. DBCO reacts with azide-bearing compounds or biomolecules to form a stable triazole linkage without copper catalysts. It could be used as a quantum yield standard. Hydrophilic PEG spacer increases solubility in aqueous media and reduces steric hindrance during binding. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Fluorescein-PEG4-Mal is a xanthene dye containing a maleimide group, which selectively reacts with free thiol, sulfhydryl, or mercapto group via Michael addition to form a stable carbon sulfur bond. It could be used as a quantum yield standard. Hydrophilic PEG spacer increases solubility in aqueous media and reduces steric hindrance during binding. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Fluorescein-PEG4-Propargyl is a xanthene dye that reacts with terminal azide via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker. It is a popular labeling dye used in Click Chemistry reactions. It could be used as a quantum yield standard. Hydrophilic PEG spacer increases solubility in aqueous media and reduces steric hindrance during binding. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Fluorescein-PEG8-Propargyl is a xanthene dye that reacts with terminal azide via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker. It is a popular labeling dye used in Click Chemistry reactions. It could be used as a quantum yield standard. Hydrophilic PEG spacer increases solubility in aqueous media and reduces steric hindrance during binding. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.