Chemicals & Small Molecules

SPY555-FastAct_X is a bright, far red, fluorogenic & non toxic F-actin stain based on our SPY™ dyes series. SPY555-FastAct_X’s carefully optimized actin ligand allows to label Factin in live cells with very high specificity. SPY555-FastAct_X can label very fast actin dynamics but lacks undesired F-actin stabilization side effect. The probe does not require any genetic manipulation, transfection or overexpression of fluorescent proteins. SPY555-FastAct_X is based on a low phototoxicity, bright & highly photostable SPY555 fluorophore which is far superior than fluorescent proteins. SPY555-FastAct_X enables multicolor imaging with SPY505, SPY595, PY620, SPY650, SPY700, GFP or mcherry. SPY555-FastAct_X can be imaged with standard Cy3filterset. It can be used for widefield, confocal, SIM or STED imaging of living cells and tissue. Contains 1 vial of SPY555-FastAct_X (lyophilized)

PMSF (Legacy Tebubio ref. 282T0789). Phenylmethanesulfonyl fluoride (PMSF (Phenylmethylsulfonyl fluoride)) is an enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthetase complex.

GolgiTrack™ Red is a cell-permeable, non-fixable, red-fluorescent dye that selectively stains Golgi apparatus in live cells. This dye has an excitation and emission maximum of 582/592 nm and can be efficiently excited using a TRITC filter. GolgiTrack™ Red can also be used in sphingolipid transport and metabolism studies. The GolgiTrack™ probes are also available in green color: GolgiTrack™ Green.