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Activators & Inhibitors

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    Results for Activators & Inhibitors ( 71835 )

      • BAY 61-3606

        Ref: T4263
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg, 1 mL, 2 mg
        From: €58.00

        BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src.

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      • NADPH tetrasodium salt

        Ref: T7092
        Sizes: 100 mg, 50 mg, 200 mg
        From: €57.00

        NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of biological reactions. NADPH tetrasodium salt is also an endogenous inhibitor of ferroptosis.

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      • JSH-150

        Ref: T8484
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg
        From: €35.00

        JSH-150 is a highly selective CDK9 inhibitor with an IC50 of 1 nM.

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      • PEG 6000

        Ref: 1088-1kg
        Sizes: 1kg
        From: €36.00

        Polyethylene glycol Water-soluble and non-toxic polymer. Increases solubility of therapeutic proteins and peptides.

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      • Stemolecule LDN-193189 (2 mg)

        Ref: 04-0074
        Sizes: 2 mg
        From: €354.00

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      • Tideglusib

        Ref: T3067
        Sizes: 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL, 200 mg
        From: €45.00

        Tideglusib (NP031112), a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3), is with anti-inflammatory and neuroprotective activities.

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      • XAV-939

        Ref: 10-1186
        Sizes: 5 mg, 25 mg
        From: €70.00

        Activity: Tankyrase inhibitor, Cardiomyogenesis inducer . Function/Pharmacology: Tankyrase inhibitor (IC50=11 and 4 nM for TNKS1 and 2 respectively). Antagonizes wnt signaling via stimulation of ß-catenin degradation and stabilization of actin.1 Robustly induces cardiomyogenesis of stem cells.2 Cell Permeable Chemical Name: 2-[4-(Trifluoromethyl)phenyl]-7,8-dihydro-5H-thiino[4,3-d]pyrimidin-4-ol

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      • SB-431542

        Ref: 10-2443
        Sizes: 5 mg, 25 mg
        From: €98.00

        Activity: ALK4,5 and 7 inhibitor . Function/Pharmacology: Potent and selective ALK4, ALK5 and ALK7 inhibitor (TGFβ superfamily Type I activin receptor-like kinase). (ALK5 IC50 = 94 nM)1,2. Inhibits TGFβ-induced proliferation of human osteosarcoma cells3. Ehances growth and integrity of embryonic stem cell-derived endothelial cells4. A frequently used agent employed in numerous stem cell differentiation protocols5. Cell permeable. Chemical Name: 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide

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      • 3-Methyladenine

        Ref: 10-2686
        Sizes: 100 mg, 20 mg
        From: €42.00

        Activity: Autophagosome inhibitor . Function/Pharmacology: Inhibits autophagy by blocking autophagosome formation via inhibition of type III phosphatidylinositol 3-kinases (PI-3K)1,2. Protects 1321N1 astrocytoma cells against pyocyanin and hydroxyphenazine-induced toxicity3. Enhances celastrol-induced apoptosis in human pancreatic cancer cells4. Chemical Name: 3-Methyl-3H-purin-6-amine

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