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Activators & Inhibitors

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    Results for Activators & Inhibitors ( 70846 )

      • Nitroaspirin

        Ref: T16328
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: €102.00

        Nitroaspirin (Legacy Tebubio ref. 282T16328). Nitroaspirin (NCX 4016) is a nitric oxide donor and a nitro-derivative of Aspirin that inhibits cyclooxygenase. It induces cell cycle arrest and apoptosis in Cisplatin-resistant human ovarian cancer cells by down-regulating EGFR/PI3K/STAT3 signaling and modulating Bcl-2 family proteins. Additionally, Nitroaspirin possesses antithrombotic and antiplatelet properties and acts as a direct and irreversible inhibitor of COX-1.

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      • Nitroflurbiprofen

        Ref: T16329
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: €88.00

        Nitroflurbiprofen (Legacy Tebubio ref. 282T16329). Nitroflurbiprofen (Nitroxybutyl flurbiprofen) is a NO-releasing COX inhibitor and modulates the increased intrahepatic vascular tone in portal hypertensive cirrhotic rats.

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      • β-Carotene

        Ref: T1633
        Sizes: 100 mg, 50 mg, 500 mg, 1 mL * 5 mM (in DMSO)
        From: €45.00

        β-Carotene (Legacy Tebubio ref. 282T1633). β-Carotene (Provitamin A) is a naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene inhibits free-radical damage to DNA.

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      • Nitromifene

        Ref: T16330
        Sizes: 25 mg, 100 mg, 50 mg
        From: €1,726.00

        Nitromifene (Legacy Tebubio ref. 282T16330). Nitromifene is the estrogen receptor antagonist.

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      • NK-252

        Ref: T16331
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: €38.00

        NK-252 (Legacy Tebubio ref. 282T16331). NK-252 is a potential activator of Nrf2. It has great Nrf2-activating potential.

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      • NKH477

        Ref: T16332
        Sizes: 1 mg
        From: €73.00

        NKH477 (Legacy Tebubio ref. 282T16332). NKH477 (Colforsin dapropate hydrochloride) is a derivative of forskolin with antidepressant activity. It inhibits ACh-induced Ca2+ mobilization by acting on ionomycin-sensitive storage sites. NKH477 is an adenylyl cyclase activator with bronchodilatory effects, inhibiting the production of CTL, T-cell proliferation in mixed lymphocyte reactions (MLR), as well as IL-2 production and mitogen responses.

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      • NKY80

        Ref: T16333
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: €45.00

        NKY80 (Legacy Tebubio ref. 282T16333). NKY80 regulates the adenylyl cyclase catalytic activity in heart and lung tissues. NKY80 is a non-competitive inhibitor of adenylyl cyclase type V isoform (IC50s: 8.3 µM, 132 µM, and 1.7 mM for type V, III and II, respectively).

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      • NMS-P515

        Ref: T16334
        Sizes: 25 mg, 100 mg, 50 mg
        From: €1,487.00

        NMS-P515 (Legacy Tebubio ref. 282T16334). NMS-P515 is an effective, orally active, and stereospecific PARP-1 inhibitor (Kd: 16 nM and an IC50: 27 nM (in Hela cells)). It has anti-tumor activity.

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      • Nonaethylene glycol monododecyl ether

        Ref: T16335
        Sizes: 1 g, 100 mg, 50 mg, 500 mg, 1 mL * 10 mM (in DMSO)
        From: €35.00

        Nonaethylene glycol monododecyl ether (Legacy Tebubio ref. 282T16335). Nonaethylene glycol monododecyl ether (Polidocanol) is a nonionic surfactant and polyethylene glycol (PEG) detergent. It can be used to form initial coalesced O/W emulsion droplets and for protein separation and purification.

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