Filters
Results for Activators & Inhibitors ( 70846 )
- From: €40.00
NU6140 (Legacy Tebubio ref. 282T16359). NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM). It shows 10- to 36-fold selectivity over other CDKs. NU6140 also effectively inhibits Aurora A and Aurora B (IC50s: 67 and 35 nM, respectively). It also enhances the apoptotic effect and has anti-cancer activity.
- Ref: T1636Sizes: 25 mg, 100 mg, 50 mg, 500 mg, 200 mg, 1 mL * 10 mM (in DMSO)
- From: €57.00
NVP-2 (Legacy Tebubio ref. 282T16363). NVP-2 is an effective and selective ATP-competitive cyclin-dependent kinase 9 (CDK9) probe. NVP-2 induces cell apoptosis. NVP-2 inhibits CDK9/CycT activity (IC50: 0.514 nM). NVP-2 shows inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases (IC50: 0.584 μM, 0.706 μM, and 0.605 μM, respectively).