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    Results for Activators & Inhibitors ( 70846 )

      • Ref: T16402
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: €45.00

        Org-26576 (Legacy Tebubio ref. 282T16402). Org-26576 is a positive allosteric modulator of the AMPA receptor.

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      • Ref: T16403
        Sizes: 1 mg
        From: €226.00

        Org41841 (Legacy Tebubio ref. 282T16403). Org41841 is an agonist of luteinising hormone/chorionic gonadotropin receptor and thyroid stimulating hormone receptor (EC50s: 0.2 and 7.7 μM, respectively) and can be used to study hyperthyroidism.

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      • Ref: T16404
        Sizes: 25 mg, 100 mg, 50 mg
        From: €2,747.00

        ORIC-101 (Legacy Tebubio ref. 282T16404). ORIC-101 is a highly effective and selective glucocorticoid receptor antagonist (EC50: 5.6 nM). It also has anti-cancer activity.

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      • Ref: T16405
        Sizes: 25 mg, 100 mg, 50 mg
        From: €1,726.00

        Ornidazole diol (Legacy Tebubio ref. 282T16405). Ornidazole diol is a diol produced through ornidazole rapidly hydrolyzing in basic solutions.

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      • Ref: T16406
        Sizes: 25 mg, 100 mg, 50 mg
        From: €781.00

        Orvepitant maleate (Legacy Tebubio ref. 282T16406). Orvepitant maleate is an effective, selective, and well-tolerated neurokinin-1 receptor (NK-1) antagonist (pKi: 10.2 for human neurokinin-1 receptor). Orvepitant maleate has the potential for depressive disorder and chronic refractory cough (CRC) treatment. Orvepitant maleate can across the blood-brain barrier.

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      • Ref: T16407
        Sizes: 5 mg

        Osajin (Legacy Tebubio ref. 282T16407). Osajin is the major bioactive iso avone present in the fruit of Maclura pomifera. It has antitumor, antioxidant, and anti-inflammatory activities.

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      • Ref: T16408
        Sizes: 25 mg, 100 mg, 50 mg
        From: €2,520.00

        Osanetant (Legacy Tebubio ref. 282T16408). Osanetant produces anxiolytic- and antidepressant-like effects. Osanetant is a selective NK3 receptor antagonist. It is researched for schizophrenia.

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      • Ref: T16409
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: €39.00

        OSMI-1 (Legacy Tebubio ref. 282T16409). OSMI-1 is an O-GlcNAc transferase (OGT) inhibitor (IC50=2.7 μM) that is orally active and cell-permeable. OSMI-1 inhibits protein O-GlcNA acetylation without qualitatively altering cell-surface N- or O- linked glycans.

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      • Ref: T1641
        Sizes: 25 mg, 100 mg, 50 mg, 10 mg, 200 mg
        From: €35.00

        Strontium ranelate (Legacy Tebubio ref. 282T1641). Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both increases deposition of new bone by osteoblasts and reduces the resorption of bone by osteoclasts. It is therefore promoted as a "dual action bone agent" (DABA) indicated for use in the treatment of severe osteoporosis.

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