Skip to main content
Customer Service: +31 072-572 21 00
Contact us
(0)
My Wishlist
(0)
My Wishlist
(0)
My WishlistContact us
Products banner

Activators & Inhibitors

Filters

    Results for Activators & Inhibitors ( 70847 )

      • PF-05180999

        Ref: T16484
        Sizes: 2 mg
        From: €94.00

        PF-05180999 (Legacy Tebubio ref. 282T16484). PF-05180999 (PF-999) is a selective and potent phosphodiesterase 2A (PDE2A) inhibitor that enhances long-term memory in a contextual fear conditioned reflex model in rats.

        Product detail

      • PF-05198007

        Ref: T16485
        Sizes: 5 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: €100.00

        PF-05198007 (Legacy Tebubio ref. 282T16485). PF-05198007 is a compound with a similar pharmacodynamic profile to PF-05089771. PF-05198007 is an effective and selective arylsulfonamide Nav1.7 inhibitor.

        Product detail

      • PF-05241328

        Ref: T16487
        Sizes: 25 mg, 100 mg, 50 mg
        From: €1,726.00

        PF-05241328 (Legacy Tebubio ref. 282T16487). PF-05241328 is an effective and selective inhibitor of human Nav1.7 voltage-dependent sodium channels (IC50: 31 nM).

        Product detail

      • PF-06263276

        Ref: T16488
        Sizes: 5 mg, 100 mg, 50 mg, 2 mg
        From: €105.00

        PF-06263276 (Legacy Tebubio ref. 282T16488). PF-06263276 is an effective and selective inhibitor of pan-JAK. It also has IC50s of 2.2 nM, 23.1 nM, 59.9 nM and 29.7 nM for JAK1, JAK2, JAK3, and TYK2, respectively.

        Product detail

      • Darigabat

        Ref: T16489
        Sizes: 1 mg, 5 mg
        From: €56.00

        Darigabat (Legacy Tebubio ref. 282T16489). Darigabat (PF-06372865) is an orally active and selective GABAA receptor modulator that crosses the blood-brain barrier and exhibits anxiolytic activity, with Ki values of 2.9 nM, 21 nM, and 134 nM for α2, α1 PAM, and α2 PAM, respectively.Darigabat is used in the study of anxiety disorders and epilepsy.

        Product detail

      • Tenofovir

        Ref: T1649
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: €42.00

        Tenofovir (Legacy Tebubio ref. 282T1649). Tenofovir (GS 1278) is an adenine analog REVERSE TRANSC-RIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIVIRAL AGENTS, due to the emergence of ANTIVIRAL DRUG RESISTANCE when it is used alone.

        Product detail

      • PF-06380101

        Ref: T16490
        Sizes: 25 mg, 100 mg, 50 mg
        From: €1,121.00

        PF-06380101 (Legacy Tebubio ref. 282T16490). PF-06380101 is an auristatin microtubule inhibitor and is a cytotoxic Dolastatin 10 analogue. When compared to other synthetic auristatin analogues that are used in the preparation of ADCs, PF-06380101 displays excellent potencies in tumor cell proliferation assays and differential ADME properties.

        Product detail

      • PF-06446846 hydrochloride

        Ref: T16491
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: €104.00

        PF-06446846 hydrochloride (Legacy Tebubio ref. 282T16491). PF-06446846 hydrochloride, an orally active and highly selective inhibitor, targets Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) translation by inducing ribosomal stalling at approximately codon 34, effectively suppressing PCSK9 expression.

        Product detail

      • PF-06459988

        Ref: T16492
        Sizes: 1 mg
        From: €170.00

        PF-06459988 (Legacy Tebubio ref. 282T16492). PF-06459988 is a novel, effective, orally active, irreversible, and selective epidermal growth factor receptor (EGFR) mutant inhibitor. PF-06459988 has high efficiency and high affinity for EGFRs double mutants containing T790M, and has minimal activity against WT EGFR. PF-06459988 makes a candidate drug for the treatment of cancer.

        Product detail