Results for Activators & Inhibitors ( 70846 )
- From: €1,896.00
Vandetanib Fumarate (Legacy Tebubio ref. 282T1656L). Vandetanib Fumarate is an orally available tyrosine kinase inhibitor. Vandetanib Fumarate works by blocking RET (REarranged during Transfection), vascular endothelial growth factor receptor (VEGFR-2, VEGFR-3), and epidermal growth factor receptor and to a lesser extent VEGFR-1, which are important targets in thyroid cancer (TC).
Pralnacasan (Legacy Tebubio ref. 282T16570). Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ. Pralnacasan is an effective, non-peptide, and orally active interleukin-1β converting enzyme inhibitor (Ki: 1.4 nM). Pralnacasan has the potential for osteoarthritis and rheumatoid arthritis treatment.
- From: €35.00
Pranidipine (Legacy Tebubio ref. 282T16571). Pranidipine (OPC-13340) is a novel, long-acting 1,4-dihydropyridine calcium channel blocker with antihypertensive activity. It enhances acetylcholine-induced relaxation in the presence of endothelium and nitroglycerin-induced relaxation in the absence of endothelium.
- From: €1,726.00
Prasugrel (Maleic acid) (Legacy Tebubio ref. 282T16572). Prasugrel Maleic acid is an orally active and potent P2Y12 receptor antagonist and inhibits ADP-induced platelet aggregation. Prasugrel Maleic acid is a thienopyridine and prodrug. Prasugrel Maleic acid also inhibits platelet function.
- From: €48.00
Pregnenolone monosulfate sodium salt (Legacy Tebubio ref. 282T16574). Pregnenolone monosulfate sodium salt is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium salt can protect the brain from cannabis intoxication. Pregnenolone monosulfate sodium salt acts as a signaling-specific inhibitor of the cannabinoid CB1 receptor. Pregnenolone monosulfate sodium salt also inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors.
- From: €45.00
Pritelivir mesylate hydrate (Legacy Tebubio ref. 282T16575). Pritelivir mesylate hydrate is active against herpes simplex virus types 1 and 2 (IC50: 0.02 μM against HSV1-2). Pritelivir mesylate hydrate is an inhibitor of the viral helicase-primase complex. Pritelivir mesylate hydrate shows antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection.