Chemicals

Phosphatidylcholine (PC) Lipid Microparticles are beads with attached phosphatidylcholine. The PC headgroups are exposed and available for biological interactions. PC is primarily an extracellular phospholipid of cell membranes and is a key structural lipid. This product is intended as a negative control when using PS lipid microparticles in apoptosis or in phagocytosis studies.Technical Notes1. Total lipid concentration is approximately 1 μmol per 1 mg particles.2. Particle comprised of a silica core and is 3 µm.

Phosphatidylserine (PS) Lipid Microparticles are beads with attached phosphatidylserine. Phosphatidylserine (PS) is an anionic intracellular phospholipid component of the cell membrane and is involved in cell signaling. PS coated microparticles are intended as a positive control for apoptosis or in phagocytosis studies.Technical Notes1. Total lipid concentration is approximately 1 μmol per 1 mg particles.2. Particle comprised of a silica core and is 3 µm.

Ethane-1,2-diamine is a widely used building block in chemical synthesis. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

PC-Maleimide-OH

1-(pentan-5-ol)-2-hydroxyl-3,4-bis(TBDMS-hexane)

Pasteurella Multocida Toxin

PERTUSSIS TOXINS AND VIRULENCE FACTORS

Gliocidin (62289-81-0) is a nicotinamide-mimetic prodrug that targets de novo purine biosynthesis vulnerability in glioblastoma (IC50 = 150 nM). Gliocidin was converted via the NAD+ salvage pathway to gliocidin-adenine dinucleotide with directly interfered with the activity of IMPDH2 resulting in guanylate depletion and cell death. Displays strong blood brain barrier permeability and suppression of glioblastoma in athymic nude mice. Gliocidin showed synergistic effects with temozolomide. Inhibitor of the SARS 3CLPRO protease.