Results for Click Chemistry ( 996 )
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Bis-Sulfone-PEG8-acid is a PEG linker with a sulfone and acid end group. The sulfone group can be conjugated with thiol groups of proteins. The terminal carboxylic acid can react with primary amines in the presence of activators such as EDC and HATU to from stable amide bonds. The hydrophilic PEG chain increases the water solubility of the compound in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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TCO-PEG4-Val-Cit-PAB-PNP is a cleavable peptide linker. The Val-Cit linker will specifically be cleaved by Cathepsin B. PNP is a good leaving group in nucleophilic reaction. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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DBCO-PEG4-Val-Cit-PAB-PNP is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. PNP can be substituted by amine-containing payload. DBCO enable click chemistry with azide molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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5-azidopentan-1-ol is a linker containing an azide group and a terminal hydroxyl group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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Tos-pentane-azide is a linker containing an azide group and a tosyl group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The tosyl group is a good leaving group for nucleophilic substitution reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.