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5-Carboxytetramethylrhodamine Azide (5-TAMRA-Azide) is a reporter reagent that allows efficient fluorescent labeling of nucleic acids by click bioconjugation. It is often used as FRET-acceptor in combination with FAM. Just like many rhodamine-based dyes, it is quite photostable between pH 4 and 9. It shows identical spectral properties to Alexa Fluor® 555 or DyLight 549 dyes.