Lipids & Polymers

m-PEG-NH2, MW 2,000 is a monofunctional PEG polymer containing an amine terminus which can undergo coupling reaction with an activated NHS ester to form a stable amide bond. Reagent grade, for research purpose.

m-PEG-NH2, MW 1,000 is a PEGylation reagent with a terminal amine which is reactive with activated NHS esters to form a stable amide bond. Reagent grade, for research purpose.

HO-PEG-amine, MW 3,400 is a heterobifunctional polyPEG. The NH2 is reactive with succinimidyl ester. The -OH can be used for futher functionalization. Reagent grade, for research purpose.

HO-PEG-amine, MW 2,000 reacts with an active NHS or PFP ester to form a stable amide linkage. The hydroxyl group can be deprotonated readily for chemical modification. Reagent grade, for research purpose.

m-PEG8-(CH2)12-phosphonic acid ethyl ester is a PEG linker containing phosphonic acid ethyl ester. The hydrophilic PEG linker increases the water solubility properties of the compound. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-(Amino-PEG4)-N-Biotin-PEG4-acid is a 3-arm biotinylation reagent with terminal amine(NH2) and carboxylic acid moieties. The amine group can react with activated NHS esters. Carboxylic acid can conjugate with primary amines in the presence of activators such as EDC or HATU to form stable amide bonds. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) consists of two terminal propargyl groups and an aminooxy group. The propargyl groups reacts with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry. The aminooxy group is reactive towards aldehydes to form oxime bonds. If a reductant is used, it will form a hydroxylamine linkage. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.

DSPE-PEG5-azide is a heterobifunctional PEG linker. The DSPE-PEGs have been FDA approved for medical applications. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The hydrophilic PEG linker increases the water solubility of the overall compound allowing for the delivery of the drug. The azide group can undergo copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-Mal-N-bis(PEG4-acid) is an Maleimide PEG reagent with two terminal carboxylic acids and a maleimide (Mal) group. Maleimide (Mal) reacts specifically with sulfhydryl groups to form a stable thioether linkage when the pH is between 6.5 and 7.5. The terminal carboxylic acids can conjugate with iamine-containing molecule in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.