Lipids & Polymers

Mal-PEG-Mal, MW 5,000 is a PEG-based crosslinking agent that contains thiol reactive functional group. The maleimide groups can react with thiols between pH 6.5 to 7.5 to form a stable thioether bond. Reagent grade, for research purpose.

HO-PEG-Mal, MW 3,400 is a linear heterobifunctional polyPEG. The maleimide can react with thiol groups at pH 6.5 to 7.5 to form a thioether bond. The hydroxyl group can be further derivatized. Reagent grade, for research purpose.

HO-PEG-Mal, MW 5,000 is a maleimide PEGylation reagent which is reactive with thiol at pH 6.5 to 7.5 to form a stable thioether linkage. The hydroxyl group enables further functionalization. Reagent grade, for research purpose.

m-PEG-thiol, MW 5,000 selectively reacts with maleimide, SPDP, and disulfides. Thiol also shows strong affinity to transition metal via formation of metal thiolate complex. Reagent grade, for research purpose.

m-PEG-thiol, MW 10,000 is a thiol PEG polymer which is reactive with maleimide, SPDP, alkene, and disulfides. Thiol group can also interact with transition metal forming a metal-thiolate complex. Reagent grade, for research purpose.

m-PEG-thiol, MW 20,000 is a maleimide reactive PEG polymer via formation of a stable thioether bond. Reagent grade, for research purpose.

DBCO-NHCO-PEG4-NHS ester is a PEG linker containing NHS ester that is able to react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and can also provide a long and flexible connection that minimizes steric hindrance during ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DSPE-PEG4-acid is a PEG linker containing DSPE and carboxylic acid moieties. The DSPE-PEGs have been FDA approved for medical applications. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The hydrophilic PEG linker increases the water solubility of the overall compound allowing for the delivery of the drug. The carboxylic acid group can react with primary amines using activators such as EDC and HATU to form stable amide bonds. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

m-PEG5-succinimidyl carbonate is a PEG linker with an attached succinumidyl carbonate group. The succinimidyl carbonate group is a good leaving group and commonly reacts with amine nucleophiles. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.