Lipids & Polymers

Propargyl-PEG5-CH2CO2tBu enables the formation of triazole linkages with azide compounds or biomolecules in copper catalyzed Click Chemistry reactions. The t-butyl group can be hydrolyzed under acidic conditions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

(2-pyridyldithio)-PEG4-propargyl is a PEG linker which contains a pyridyl disulfide moiety and a propargyl group. The pyridyl disulfide group can react with thiol groups of proteins over a wide range of pH levels. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

APN-C3-PEG4-azide is a heterobifunctional linker containing an APN moiety with exquisite chemoselectivity for cysteine and an azide group. The superior stability of APN-cysteine conjugates in aqueous media, human plasma, and living cells makes this new thiol-click reaction a promising methodology for applications in bioconjugation. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-PEG8-Acid is a click chemistry building block. In the presence of activators (e.g. EDC, or HATU), it can be used to conjugate with amine-containing molecule. PEG8 spacer increases the aqueous solubility of the compound. Methyltetrazine enable fast click chemistry with TCO ((trans-cycloctene) under mild condition Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-PEG8-NHS Ester is a PEG active NHS ester, which is very reactive with amine(NH2) cotaining entity. The hydrophilic PEG spacer is transferrable to the labeled molecule, reducing aggregation of labeled proteins stored in solution. Methyltetrazine enable click chemistry with TCO (trans-cycloctene). Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-(acid-PEG3)-N-bis(PEG3-amine) is a 3-arm PEG reagent that is reactive toward activated NHS esters, Carboxylic acid group (CO2H) is reactive with primary amine groups in the presence of HATU or EDC. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

APN-C3-PEG4-alkyne is a heterobifunctional linker containing an APN moiety with exquisite chemoselectivity for cysteine and an alkyne group. The superior stability of APN-cysteine conjugates in aqueous media, human plasma, and living cells makes this new thiol-click reaction a promising methodology for applications in bioconjugation. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azido-Phenyl-Amido-S-S-Sulfo-NHS is a water-soluble, cleavable crosslinker. The aryl azide can be photo-activated with UV light (250 to 350 nm) for conjugation with biomolecules. The sulfo-NHS ester improves water solubility and can be reacted with nucleophiles for labeling applications. The disulfide bond can be cleaved via reducing agents. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Methyltetrazine-PEG12-NHS ester is an aqueous soluble building block containing a methyltetrazine group. This compound can react with primary amines such as the side chain of lysine residue or aminosilane-coated surfaces at neutral or slightly basic pH to form covalent bonds. Methyltetrazine is reaactive with TCO via click chemistry. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.