N-(PEG4-acid)-N-bis(PEG4-t-butyl ester) is a branched PEG linker with a terminal carboxylic acid group which is reactive with amine molecules in the presence of HATU. The two t-butyl ester groups can be hydrolyzed under acidic conditions to obtain free acids.
N-(NHS-PEG3)-N-bis(PEG3-azide), HCl salt is a branched PEG linker containing a NHS ester that is reactive with amine-containing moieties and two azides highly reactive in click chemistry with strained cyclooctynes or other alkynes.
N-(PEG4-NHS ester)-N-bis(PEG4-t-butyl ester) represents a branched PEG linker containing two t-butyl ester moieties which can be deprotected under acidic conditions and an NHS ester moiety to react directly and efficiently with amine-containing entities.
N-(PEG4-NHS ester)-N-bis(PEG4-acid) is a branched PEG linker containing two terminal carboxylic groups which form stable amide bonds with amine-bearing compounds in the presence of HATU. The NHS ester reacts easily with primary amine groups. The PEG spacers impart water solubility.
L2, also known as nonadecanedioic acid,10-[[3-(dimethylamino)propyl](1-oxooctyl)amino]-,1,19-bis(2-hexyloctyl) ester, serves as an MC3 analogue used in the development of lipid nanoparticles (LNPs).
L3, also known as 1,19-Bis(2-hexyldecyl)10- [[3-(dimethylamino)propyl](1-oxooctyl)amino]nonadecanedioate, is a derivative of MC3 that can be exploited for creating lipid nanoparticles (LNPs).
L13, also known as 1-Octylnonyl 8-[(2-hydroxyethyl)[4-(nony loxy)-4-oxobutyl]amino]octanoate, may be applied in the generation of lipid nanoparticles (LNPs).
L14, also known as 1-Octylnonyl 8-[(2-hydroxyethyl)[8-[(1-methylnonyl)oxy]-8-oxooctyl]amino]octanoate, is an SM-102 analog used in the formation of lipid nanoparticles (LNPs).
