Lipids & Polymers

DBCO-PEG4-C3-sulfonic acid serves as a bifunctional PEG linker. The DBCO click chemistry handle conjugates with azides on target molecules to form stable triazole linkages. The sulfonic acid can participate in esterification, halogenation and displacement reactions.

Propargyl-PEG-t-butyl ester, MW 2,000 functions as a PEG polymer containing a propargyl for copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage, and the t-butyl group can be deprotected under acidic conditions.

An ionizable lipid featuring biodegradable ester linkages and saturated branched lipid tails. These lipids may be formulated into lipid nanoparticles for drug delivery research. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DSPE-Fluor 488 is a fluorescent lipid The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences.

Propargyl-PEG5-Ms represents a bifunctional linker possessing a proparygyl group reactive towards azides in copper (I) click chemistry to form stable triazoles with the target compound as well as a mesyl group which is a good leaving group for nucleophilic reactions.

An ionizable lipid featuring biodegradable ester linkages and monounsaturated palmitoleic acid tails. These lipids may be formulated into lipid nanoparticles for drug delivery research. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

A tetrahydropyran ether (THP)-protected PEG2000 terminated with a hydroxyl group. The exposed hydroxyl group may be used for functionalization. The THP protecting group may be removed with a mild acid catalyst to expose an additional hydroxyl group for further modifications. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

An asymmetric analog of CL15H6 featuring one branched, saturated tail and one palmitoleic acid tail. These lipids may be formulated into lipid nanoparticles for drug delivery research. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Cbz-GGFG-Bn, as a potent and selective mTORC1 signaling inhibitor, plays a crucial role as a cytotoxic payload in the development of antibody-drug conjugates (ADCs). Reagent grade, for research purpose.