Lipids & Polymers

PEG4-SATA (S-actyl-PEG 4-NHS ester) features a water-soluble PEG4 spacer between a protected thiol and an NHS ester, allowing it to thiolate molecules with amines and react in aqueous solutions without needing organic solvents. The PEG spacer also reduces protein aggregation and precipitation, and the acetyl-protecting group can be easily removed with hydroxylamine hydrochloride to free the sulfhydryl moiety. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

PEG8-SATA (S-acetyl-PEG8-NHS ester) includes a water-soluble PEG8 chain between a protected thiol and an NHS ester, permitting it to thiolate molecules with amines and react in aqueous solutions without needing organic solvents. The PEG chain also decreases protein aggregation and precipitation, and the acetyl-protecting group can be easily removed with hydroxylamine hydrochloride to expose the sulfhydryl moiety. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

PEG12-SATA (S-acetyl-PEG12-NHS ester)

DBCO-TFP ester is an amine-reactive, labeling reagent used to modify proteins, antibodies, and other amine-containing biopolymers. The highly reactive DBCO group can be used in copper-free click reactions. The TFP ester can react with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Bromoacetamido-PEG4-TFP ester represents a PEG linker containing a bromo group, which is a good leaving group for nucleophilic substitution reactions, and the TFP ester, which can react with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. The PEG4 spacer imparts water-solubility. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Bromoacetamido-PEG4-amido-DBCO functions as a PEG linker including a bromo group, which is a good leaving group for nucleophilic substitution reactions, and DBCO, which is a highly reactive cycloalkyne which is commonly used for copper-free Click Chemistry reactions. The PEG4 units enhance the hydrophilicity of the compound. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Bromoacetamido-PEG12-amido-DBCO serves as a PEG linker with a bromo group that is a good leaving group for nucleophilic substitution reactions and a highly reactive DBCO for copper-free click reactions. The PEG12 chain improves the aqueous solubility of the molecule. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Bromoacetamido-PEG11-azide is a bifunctional linker comprised of bromine (Br), which can be used as a leaving group for nucleophilic substitution reactions, and azide group, which can undergo copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN. The water solubility of the molecule is increased by the PEG chain. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Mal-PEG36-NHS ester is a PEG linker containing a maleimide group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. Water solubility is elevated via the PEG36 units. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.