Lipids & Polymers

Biotin-PEG12-DBCO is a biotinylating reagent comprised of DBCO, a click chemistry handle that is frequently used to conjugate with azides on target molecules, and biotin, which is useful for affinity-based applications such as pull-down assays or for ligating with streptavidin proteins. The PEG12 imparts the hydrophilicity of the compound. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Fmoc-Val-Cit-PAB-MMAF serves as an ADC linker with an enzymatically cleavable Val-Cit site. The Val-Cit will specifically be cleaved by Cathepsin B. Fmoc can be deprotected under basic conditions. MMAF is a synthetic antineoplastic agent which may be employed as a cytotoxic payload. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DBCO-PEG-MethylTetrazine, MW 10,000 functions as a clickable PEG polymer possessing methyltetrazine, a terminal TCO reactive group, and DBCO, a click chemistry handle that is frequently used to conjugate with azides on target molecules to form stable triazole linkages. Methyltetrazine can convert azido-containing peptides or proteins into tetrazine-modified peptides or proteins without catalysts or axillary reagents. The hydrophilic PEG chain increases the water solubility of the compound. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DBCO-PEG-MethylTetrazine, MW 5,000 serves as a clickable PEG polymer including methyltetrazine and DBCO, which is frequently used to conjugate with azides on target molecules to form stable triazole linkages. Methyltetrazine reacts with TCO and can convert azido-bearing peptides or proteins into tetrazine-modified peptides or proteins without catalysts or axillary reagents. The 5k polyPEG enhances the hydrophilicity of the compound. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DBCO-PEG-TCO, MW 5,000 is a polyPEG reagent containing TCO, which is a click chemistry handle that readily reacts with tetrazine groups on a target molecule, and DBCO, which is a click chemistry handle that readily reacts with azide groups without the need for copper. The 5k PEG polymer greatly improves the solubility of the compound in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

C12-PEG11-alcohol can be used as a reference standard in endotoxin testing of lipids. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

A multichargeable ionizable lipid feauting two fully saturated branched tails and biodegradable ester linkages. This compound may be used in the formulation of lipid nanoparticles (LNP's) for delivery applications. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Lipid 429 is a multichargeable lipid featuring saturated branched tails, two biodegradable ester linkages, and an aliphatic amide branch adjacent to the polar head group. This compound may be used in the formulation of lipid nanoparticles (LNP's) for delivery applications. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Lipid 430 is a multichargeable lipid featuring saturated branched tails, two biodegradable ester linkages, and a BOC-protected amino head group. This compound may be used for bioconjucation or in the formulation of lipid nanoparticles (LNP's) for delivery applications. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.