Lipids & Polymers

DBCO-PEG8-NHS Ester is a click chemistry molecule cosisting of an NHS ester that is reactive specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. PEG8 spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-(Amino-PEG10)-N-bis(PEG10-azide) is a PEG reagent containing a terminal amine and two azide groups. The hydrophilic PEG spacer increases solubility in aqueous media. The azide groups can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

(Amino-PEG10)-Tri-(Azide-PEG10-ethoxymethyl)-methane HCl Salt is a branched PEGylation reagent containing an amino group with three azide groups. The amino group is reactive with carboxylic acids, activated NHS esters. . The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Amino-PEG-t-butyl ester, MW 3,400 is a coupling PEG reagent which can be reacted with a succinimidyl ester under physiological condition to form an amide bond. The t-butyl ester group can be hydrolyzed under acidic or basic condition. Reagent grade, for research purpose.

Acid-PEG8-t-butyl ester is a bifunctional PEG linker with a carboxylic acid and a t-butyl ester. Carboxylic acids can be conjugated with alcohols or amines while the t-butyl ester can be hydrolyzed under acidic conditions.

DOPE-PEG-Amine, MW 1,000 is an amino phospholipid polyPEG. The polymer can self-assemble in water to form micelles and can be used to prepare liposomes or nanoparticles for drug delivery applications. Reagent grade, for research purpose.