Lipids & Polymers

Diazo Biotin-PEG3-alkyne (Legacy Tebubio ref. 282T15114). Diazo Biotin-PEG3-alkyne is a polyethylene glycol (PEG)-based linker designed specifically for the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

DNP-NH-PEG2-C2-acid (Legacy Tebubio ref. 282T15148). DNP-NH-PEG2-C2-acid is a PEG-based linker for PROTACs, which connects two essential ligands critical for PROTAC molecule formation, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

DNP-PEG3-azide (Legacy Tebubio ref. 282T15150). DNP-PEG3-azide, a PEG-based linker for PROTACs, joins two essential ligands, crucial for forming PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DNP-PEG4-acid (Legacy Tebubio ref. 282T15152). DNP-PEG4-acid is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation leveraging the ubiquitin-proteasome system within cells.

DNP-PEG4-alcohol (Legacy Tebubio ref. 282T15153). DNP-PEG4-alcohol is a PEG-based linker for PROTACs, facilitating the formation of PROTAC molecules by joining two essential ligands, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.

DNP-PEG4-NHS ester (Legacy Tebubio ref. 282T15154). DNP-PEG4-NHS ester, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

(S,R,S)-AHPC-PEG4-NH2 hydrochloride (Legacy Tebubio ref. 282T15190). (S, R, S)-AHPC-PEG4-NH2 hydrochloride is a chemically synthesized conjugate consisting of an E3 ligase ligand-linker, incorporating the VHL ligand based on (S, R, S)-AHPC, and a 4-unit PEG linker, which are specifically designed for use in PROTAC technology.

(S,R,S)-AHPC-PEG4-NH2 (Legacy Tebubio ref. 282T15190L). (S,R,S)-AHPC-PEG4-NH2 (VHL Ligand-Linker Conjugates 4) is a synthetic E3 ligase ligand-linker conjugate, consisting of a VHL ligand based on (S,R,S)-AHPC combined with a 4-unit PEG linker.

endo-BCN-PEG2-acid (Legacy Tebubio ref. 282T15221). endo-BCN-PEG2-acid, a PEG-based linker for PROTACs, connects two essential ligands necessary for PROTAC molecule formation. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.