Lipids & Polymers

HO-PEG21-OH (Legacy Tebubio ref. 282T15493). HO-PEG21-OH is a PEG-based linker for PROTACs, enabling the selective degradation of proteins by connecting two essential ligands and utilizing the ubiquitin-proteasome system within cells.

Hydroxy-PEG10-Boc (Legacy Tebubio ref. 282T15514). Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG10-Boc can be conjugated to Paclitaxel or docetaxel [2].

Hydroxy-PEG2-C2-methyl ester (Legacy Tebubio ref. 282T15516). Hydroxy-PEG2-C2-methyl ester, a polyethylene glycol (PEG)-based linker, is commonly utilized for the synthesis of proteolysis targeting chimeras (PROTACs) [1].

Hydroxy-PEG2-C2-PFP ester (Legacy Tebubio ref. 282T15517). Hydroxy-PEG2-C2-PFP ester, a PEG/Alkyl/ether-based PROteolysis TArgeting Chimeric (PROTAC) linker, is suitable for the synthesis of PROTACs.

Hydroxy-PEG4-(CH2)2-Boc (Legacy Tebubio ref. 282T15529). Hydroxy-PEG4-(CH2)2-Boc is an uncleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and can also be employed in the synthesis of PROTAC.

Hydroxy-PEG4-CH2COOH (Legacy Tebubio ref. 282T15531). Hydroxy-PEG4-CH2COOH is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the [ubiquitin-proteasome system] within cells.

Hydroxy-PEG4-O-Boc (Legacy Tebubio ref. 282T15533). Hydroxy-PEG4-O-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Hydroxy-PEG5-Boc (Legacy Tebubio ref. 282T15534). Hydroxy-PEG6-Boc, a PEG-based PROTAC linker, is utilized in PROTAC synthesis [1].

Hydroxy-PEG5-C2-methyl ester (Legacy Tebubio ref. 282T15535). Hydroxy-PEG5-C2-methyl ester, a polyethylene glycol (PEG) derived linker compound, is utilized in PROTAC (PROteolysis TArgeting Chimeras) synthesis[1].