Lipids & Polymers

Hydroxy-PEG6-acid (Legacy Tebubio ref. 282T15536). Hydroxy-PEG6-acid is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Hydroxy-PEG6-Boc (Legacy Tebubio ref. 282T15537). Hydroxy-PEG7-Boc, a PEG-based PROTAC linker, is utilized in PROTAC synthesis [1].

Iodo-PEG4-N3 (Legacy Tebubio ref. 282T15589). Iodo-PEG4-N3 is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

m-PEG-OH (MW 2000) (Legacy Tebubio ref. 282T15832). m-PEG-OH (MW 2000) is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands to form PROTAC molecules, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.

m-PEG12-amine (Legacy Tebubio ref. 282T15839). m-PEG12-amine is a PEG-based PROTAC linker and a non-cleavable 12-unit PEG ADC linker used in the synthesis of PROTACs [1] and antibody-drug conjugates (ADCs) [2].

m-PEG2-Amino (Legacy Tebubio ref. 282T15843). m-PEG2-Amino is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG4-aldehyde (Legacy Tebubio ref. 282T15867). m-PEG4-aldehyde is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.

m-PEG4-C6-phosphonic acid ethyl ester (Legacy Tebubio ref. 282T15873). m-PEG4-C6-phosphonic acid ethyl ester, a polyethylene glycol (PEG)-based linker compound, is used for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

m-PEG4-Hydrazide (Legacy Tebubio ref. 282T15879). m-PEG4-Hydrazide is a PEG-based linker for PROTACs, joining two essential ligands crucial for PROTAC molecule formation, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.