Lipids & Polymers

Mal-amido-PEG8-C2-acid (Legacy Tebubio ref. 282T15961). Mal-amido-PEG8-C2-acid (US2018339985, example 142) is a noncleavable linker for antibody-drug conjugates (ADCs) [1].

Mal-amido-PEG8-NHS ester (Legacy Tebubio ref. 282T15962). Mal-amido-PEG8-NHS ester, a PEG-based PROTAC linker, is utilized in the synthesis of PROTACs.

Mal-amido-PEG9-acid (Legacy Tebubio ref. 282T15964). Mal-amido-PEG9-acid is a PEG-based linker for PROTACs, crucial for joining two essential ligands and facilitating selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-amido-PEG9-amine (Legacy Tebubio ref. 282T15965). Mal-amido-PEG9-amine, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-N-bis(PEG4-C2-acid) (Legacy Tebubio ref. 282T15969). Mal-N-bis(PEG4-C2-acid) is a polyethylene glycol (PEG) derivative used as a PEG-based PROTAC linker for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

Mal-PEG1-Boc (Legacy Tebubio ref. 282T15974). Mal-PEG1-Boc is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG1-NHS ester (Legacy Tebubio ref. 282T15976). Mal-PEG1-NHS ester is a cleavable, PEG-based linker utilized in the synthesis of antibody-drug conjugates (ADCs) and PROTACs, serving as both an ADC linker and a PROTAC linker. [Mal-PEG1-NHS ester]

Mal-PEG2-acid (Legacy Tebubio ref. 282T15978). Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It can be conjugated to Tubulysin and its derivative cytotoxic molecule [1].

Mal-PEG2-alcohol (Legacy Tebubio ref. 282T15979). Mal-PEG2-alcohol, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.