Lipids

Docosatrienoic acid is a rare Omega-3 fatty acid; inhibits LTB4 binding to pig neutrophil membranes with an Ki of 5 μM.

Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) is a naturally polyunsaturated fatty acid in the adrenal gland, brain, kidney, and vasculature. Adrenic Acid can regulate the vascular tone in arteries of the adrenal cortex. Adrenic Acid also is an inflammation enhancer in non-alcoholic fatty liver disease.

12(Z)-Heneicosenoic acid

12(Z),15(Z)-Heneicosadienoic acid is an Omega-6 very long-chain polyunsaturated fatty acid. It is a positional isomer of heneicosadienoic acid that is rare in living organisms.

(14Z)-14-tricosenoic acid

Nervonic acid is a monounsaturated fatty acid important in the biosynthesis of myelin.

BP Lipid 374 is branched, multichargeable lipid which features a central PEG4 linkage to enhance biocompatibility. This lipid may be used in the development of lipid nanoparticles for drug delivery. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

m-PEG9-4-nitrophenyl carbonate serves as a PEG linker containing a nitrophenyl carbonate, which is readily displaced by amine nucleophiles to form carbamate bonds under mild conditions. The PEG9 chain bolsters the water solublity of the compound.

DSPE-PEG6-Mal is a PEG linker with a maleimide group, water-soluble PEG chain, a hydrophilic phosphate head with hydrophobic lipid tails. The polymer can self-assemble to form lipid bilayer in water. The phospholipid polyPEG can be used as a drug nanocarrier for administration of nutrients and therapeutic drugs, such as liposomes in mRNA or DNA vaccines. The maleimide group will react with a thiol group to form a covalent bond.