Lipids

DOTA-tris(acid)-amido-PEG24-amido-PEG24-DSPE consists of DSPE attached via hydrophilic PEG polymers to DOTA, which is used as a chelating agent for cations. The hydrophobic DSPE encapsulates hydrophobic drugs, while the hydrophilic PEG chains enhance water solubility for effective drug delivery.

Carboxyfluorescein-dPEG24-amido-dPEG24-DSPE is comprised of DSPE connected to a fluorescein, which is a universal dye applied in dye labeling. DSPE encapsulates hydrophobic drugs, while the hydrophilic PEG linkers enhance water solubility, facilitating effective drug delivery.

Biotin-PEG 4-amido-PEG24-amido-PEG24-DSPE serves as a biotinylated lipid where the hydrophobic DSPE encapsulates hydrophobic drugs, and the hydrophilic PEG linkers enhance water solubility, facilitating effective drug delivery.

DSG-PEG-DBCO, MW 3,400 represents a unique PEG lipid featuring DSG connected to a DBCO moiety via a water-soluble 3.4k polymer PEG linkage. The DBCO group can be used for copper-free Click Chemistry reactions. It is used for liposome preparation. DSG-PEG has become known for lipid nanoparticle (LNP) preparation for small interfering RNA (siRNA) delivery research. The water-soluble polyPEG aids in drug delivery.

A fully saturated ketone lipid featuring two biodegradable ester linkages to branched lipid tails. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

A multichargeable ionizable lipid feauting two fully saturated branched tails, dimethylamine head group, and biodegradable ester linkages. This compound may be used in the formulation of liposomes for delivery applications. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

m-PEG45-Glycerol represents a lengthy PEG linker where the hydroxyl group of the glycerol allows for further derivatization or replacement with other reactive functional groups. The PEG24 chain bolsters solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

m-PEG24-SSG functions as a PEG linker incorporating Sodium Starch Glycolate (SSG), the sodium salt of cross-linked carboxymethyl starch. SSG is modified for improved hydrophilicity through substitution and decreased solubility via cross-linking. The PEG24 arm enhances water-solubility. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Tos-C16-t-butyl ester contains a t-butyl ester that can be deprotected under acidic conditions and a tosyl group. Tosylates are good leaving groups that are easily displaced by nucleophiles. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.