Lipids

A multichargeable lipid featuring a bis-stearyl aliphatic amine tail group and a dimethylamine butanoate head group. This compound may be formulated into lipid nanoparticles for drug delivery applications. Reagent grade, for research purpose. Please contact us for GMP-grade.

BP Lipid 446 is a multichargeable lipid featuring three biodegrade amide tails, three amine spaces eight (8) carbon atoms long, and a central piperazine head group. This compound may be formulated into lipid nanoparticles for drug delivery applications. Reagent grade, for research purpose. Please contact us for GMP-grade.

PC Mal-PEG3-biotin functions as a photocleavable biotinylated reagent containing biotin, which has a strong binding with avidin or streptavidin for protein labeling or purification, and maleimide group, which will react with a thiol group. The PEG spacer imparts solubility in aqueous media. This structure allows for efficient photorelease of linked molecules, typically achieving over 90% cleavage in 5-25 minutes using a near-UV lamp.

3,3'-((2-hydroxyethyl)azanediyl)bis(N-(3-aminopropyl)propanamide)

Vacuolin-1 is a triazine-based chemical that inhibits Ca2+-dependent lysosomal exocytosis by preventing lysosome fusion with the plasma membrane. It uniquely targets this process without affecting other organelles or endocytic/secretory traffic. Widely utilized in research, Vacuolin-1 helps study lysosomal content release and autophagy modulation.

A useful synthetic scaffold for ionizable lipids featuring one branched and one oleic fatty acid tail. A free hydroxyl is available for further functionlization. Reagent grade, for research purpose. Please contact us for GMP-grade.

Mal-PEG12-MMAE acts as a linker attached to a payload, where the maleimide group will react with a thiol group to form a covalent bond, and the MMAE payload serves as a synthetic antineoplastic agent for targeted therapeutics. The PEG12 units elevate the molecule's water solubility.

DBCO-PEG12-TFP ester acts as a bifunctional PEG linker with a DBCO group that can be used for copper-free Click Chemistry reactions and TFP ester, which is less susceptible to undergo hydrolysis compared to NHS ester. The solubility of the compound in aqueous media is elevated via the PEG linkage.

Clickable Cholic acid