Lipids

It is a cationic lipid with high purity and excellent solubility in water. 16:0(Alkyne)-18:1 pe has been shown to activate ion channels, as well as inhibit ligand binding to receptors. It has also been used as a research tool for studying protein interactions, such as the study of peptides and antibodies. 16:0(Alkyne)-18:1 pe is an excellent candidate for use in pharmacology.

Photoclick sphingosine is a photoreactive probe for the study of sphingosine metabolism. It contains a terminal clickable alkyne moiety and a photoactivatable diazirine group that allow its interaction with sphingosine binding proteins and photo-activated cross-linking of its interacting partners, respectively. Photoclick sphingosine has been used to monitor the metabolism of sphingosine and visualize protein-lipid interaction complexes in S1PL-/- mouse embryonic fibroblasts (MEFs).