Lipids

20-(Bromoacetamido-PEG5-ethylcarbamoyl)heptadecanoic acid is a PEG linker containing Bromoacetamido and carboxylic acid groups. The bromo is a good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond. Reagent grade, for research purpose.

HO-PEG-amine HCl salt, MW 2,000 is an HCl salt of a polyPEG linker with terminal amine and hydroxy groups. The compound reacts with an active NHS or PFP ester to form a stable amide linkage. The hydroxyl group can be deprotonated readily for chemical modification. Reagent grade, for research purpose.

Azide-PEG5-c18-t-butyl ester is a PEG linker with a steric acid tail and a terminal azide group. Stearic Acid is a saturated long-chain fatty acid with an 18-carbon backbone. Azido group will react with DBCO, BCN or other Alkyne group through click chemistry. The PEG spacer increases aqueous solubility. Reagent grade, for research purpose.

4-Arm PEG5-Azide is a multiarm PEG linker containing four terminal azides. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Reagent grade, for research purpose.

N-bis(Azido-PEG8)-N-(PEG8-t-butyl ester) is a 3-arm PEG reagent with a t-butyl ester group and two azide groups. The t-butyl ester group can be deprotected under acidic conditions. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Reagent grade, for research purpose.

Amine-PEG5-c18-t-butyl ester is comprised of an octadecanedioic acid with a PEG linker and a terminal amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with activated NHS esters to form a stable amide bond. Reagent grade, for research purpose.

DSPE-PEG-endo-BCN, MW 2,000 is a click chemistry reagent with a BCN group attached to a polyPEG linker with hydrophobic lipid tails. The BCN group enables copper free click chemitry with azide-tagged molecules. Reagent grade, for research purpose.

N-bis(Amine-PEG8)-N-(PEG8-t-butyl ester) is a 3-arm PEG linker consisting of a t-butyl ester with two amino groups. The amino (NH2) groups are reactive with activated NHS esters or carboxylic acid. The t-butyl group can be deprotected under acidic conditions. Reagent grade, for research purpose.

14-(Azide-PEG5-ethylcarbamoyl)tridecanoic t-butyl ester is a PEG linker with an azide group and an alkane tail that has a terminal t-butyl ester group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl group can be deprotected under acidic conditions. The polymer can form micelles spontaneously in water. It may also be used to prepare more complex lipids for nanoparticles for drug delivery. Reagent grade, for research purpose.